Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Enzyme: UDPG:nicotinate N-glucosyltransferase

Species: Petroselinum crispum

Summary:
The enzyme catalyzing the convertion of nicotinate to its N-glucosyl conjugate has been partially purified from cell cultures of Petroselinum crispum. N-glucosylnicotinate was proposed to serve as a storage compound supported by the corresponding enzyme activity being present during the entire growth circle and the relatively short half life of about 24 hours. The enzyme, i.e. UDPG:nicotinate N-glucosyltransferase has been shown to promote free reversibility of the reaction indicating a point of regulation for the pyridine nucleotide cycling in plants and highlights the high group-transfer potential of N-glucosylnicotinate [Upmeier88].

Molecular Weight of Polypeptide: 46 kD (experimental) [Upmeier88 ]

Gene-Reaction Schematic: ?

Credits:
Created 25-Oct-2006 by Foerster H , TAIR


Enzymatic reaction of: UDPG:nicotinate N-glucosyltransferase

EC Number: 2.4.1.196

UDP-α-D-glucose + nicotinate + H+ <=> N-glucosylnicotinate + UDP

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction of enzyme catalysis.

This reaction is reversible.

In Pathways: N-glucosylnicotinate metabolism

Inhibitors (Unknown Mechanism): Zn2+ [Upmeier88] , p-chloromercuribenzoate

Kinetic Parameters:

Substrate
Km (μM)
Citations
UDP
1200.0
[Upmeier88]
nicotinate
170.0
[Upmeier88]

T(opt): 30 °C [Upmeier88]

pH(opt): 7.8-8.2 [Upmeier88]


References

Upmeier88: Upmeier B, Thomzik JE, Barz W (1988). "Enzymatic studies on the reversible synthesis of nicotinic acid-N-glucoside in heterotrophic parsley cell suspension cultures." Z. Naturforsch. 43c, 835-842.


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 20, 2014, biocyc14.