Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
twitter

MetaCyc Enzyme: cytosolic fructose-bisphosphate aldolase

Species: Zea mays

Summary:
A cytosolic enzyme with fructose-1,6-bisphosphate aldolase activity was isolated from the leaves of well developed corn (Zea mays L. Inrafrueh) plants [Schnarrenberger86]. This enzyme was separated from its plastidic homolog isolated simultaneously (see chloroplastic fructose-bisphosphate aldolase). In addition to fructose 1,6-bisphosphate, the enzyme was shown to catalyze the aldol cleavage of β-D-fructofuranose 1-phosphate. The cytosolic enzyme represented 4.5% of the total leaf aldolase activity. Additionally, this cytosol aldolase was shown to have a Km (F1,6P) value 5 times smaller than that of the chloroplast aldolase. However, the Km (F1P) values for either enzymes are relatively similar [Schnarrenberger86].

Locations: cytosol

Gene-Reaction Schematic: ?

GO Terms:

Cellular Component: GO:0005829 - cytosol [Schnarrenberger86]

Credits:
Created 17-Jan-2007 by Tissier C , TAIR


Enzymatic reaction of: fructose-1-phosphate aldolase (cytosolic fructose-bisphosphate aldolase)

EC Number: 4.1.2.13

β-D-fructofuranose 1-phosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

The reaction is favored in the direction shown.

Kinetic Parameters:

Substrate
Km (μM)
Citations
β-D-fructofuranose 1-phosphate
1.4
[Schnarrenberger86]


Enzymatic reaction of: fructose-1,6-bisphosphate aldolase (cytosolic fructose-bisphosphate aldolase)

EC Number: 4.1.2.13

fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

This reaction is reversible.

In Pathways: superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle , superpathway of anaerobic sucrose degradation , glycolysis IV (plant cytosol) , gluconeogenesis I

Kinetic Parameters:

Substrate
Km (μM)
Citations
fructose 1,6-bisphosphate
2.0
[Schnarrenberger86]


References

Schnarrenberger86: Schnarrenberger C, Kruger I (1986). "Distinction between Cytosol and Chloroplast Fructose-Bisphosphate Aldolases from Pea, Wheat, and Corn Leaves." Plant Physiol 80(2);301-304. PMID: 16664617


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Nov 21, 2014, BIOCYC13B.