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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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discounted EARLY registration ends Dec 31, 2014
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MetaCyc Enzyme: cytosolic fructose-bisphosphate aldolase

Species: Zea mays

Summary:
A cytosolic enzyme with fructose-1,6-bisphosphate aldolase activity was isolated from the leaves of well developed corn (Zea mays L. Inrafrueh) plants [Schnarrenberger86]. This enzyme was separated from its plastidic homolog isolated simultaneously (see chloroplastic fructose-bisphosphate aldolase). In addition to fructose 1,6-bisphosphate, the enzyme was shown to catalyze the aldol cleavage of β-D-fructofuranose 1-phosphate. The cytosolic enzyme represented 4.5% of the total leaf aldolase activity. Additionally, this cytosol aldolase was shown to have a Km (F1,6P) value 5 times smaller than that of the chloroplast aldolase. However, the Km (F1P) values for either enzymes are relatively similar [Schnarrenberger86].

Locations: cytosol

Gene-Reaction Schematic: ?

GO Terms:

Cellular Component: GO:0005829 - cytosol [Schnarrenberger86]

Credits:
Created 17-Jan-2007 by Tissier C , TAIR


Enzymatic reaction of: fructose-1-phosphate aldolase (cytosolic fructose-bisphosphate aldolase)

EC Number: 4.1.2.13

β-D-fructofuranose 1-phosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

The reaction is favored in the direction shown.

Kinetic Parameters:

Substrate
Km (μM)
Citations
β-D-fructofuranose 1-phosphate
1.4
[Schnarrenberger86]


Enzymatic reaction of: fructose-1,6-bisphosphate aldolase (cytosolic fructose-bisphosphate aldolase)

EC Number: 4.1.2.13

fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

This reaction is reversible.

In Pathways: superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle , superpathway of anaerobic sucrose degradation , glycolysis IV (plant cytosol) , gluconeogenesis I

Kinetic Parameters:

Substrate
Km (μM)
Citations
fructose 1,6-bisphosphate
2.0
[Schnarrenberger86]


References

Schnarrenberger86: Schnarrenberger C, Kruger I (1986). "Distinction between Cytosol and Chloroplast Fructose-Bisphosphate Aldolases from Pea, Wheat, and Corn Leaves." Plant Physiol 80(2);301-304. PMID: 16664617


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 20, 2014, biocyc14.