Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Enzyme: taurine:pyruvate aminotransferase

Synonyms: Tpa

Species: Pseudomonas aeruginosa TAU-5

Summary:
Taurine:pyruvate aminotransferase (Tpa) appears to be responsible for the transamination of taurine and pyruvate resulting in the formation of L-alanine and sulfoacetaldehyde in the taurine catabolism pathway of Pseudomonas aeruginosa. The enzyme was partially purified and through mutant studies was shown to be essential for growth with taurine. The enzyme is induced by taurine [Shimamoto79].

Locations: cytosol

Gene-Reaction Schematic: ?

GO Terms:

Cellular Component: GO:0005829 - cytosol


Enzymatic reaction of: taurine:pyruvate aminotransferase

EC Number: 2.6.1.77

pyruvate + taurine <=> L-alanine + sulfoacetaldehyde

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

This reaction is reversible.

In Pathways: taurine degradation I


References

Shimamoto79: Shimamoto G, Berk RS (1979). "Catabolism of taurine in Pseudomonas aeruginosa." Biochim Biophys Acta 569(2);287-92. PMID: 113035


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, biocyc11.