MetaCyc Enzyme: trehalose-6-phosphate phosphatase

Species: Saccharomyces cerevisiae

This is probably a specific maltose-induced phosphatase from the ADP-α-D-glucose-dependent pathway trehalose biosynthesis II, not the TPS2 phosphatase from the UDP-α-D-glucose-dependent pathway trehalose biosynthesis I [Ferreira97].

Gene-Reaction Schematic

Gene-Reaction Schematic

Revised 08-Feb-2012 by Fulcher CA, SRI International

Enzymatic reaction of: trehalose-6-phosphate phosphatase

Inferred from experiment

EC Number:

α,α-trehalose 6-phosphate + H2O → α,α-trehalose + phosphate

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

The reaction is physiologically favored in the direction shown.

In Pathways: trehalose biosynthesis II


Ferreira97: Ferreira JC, Thevelein JM, Hohmann S, Paschoalin VM, Trugo LC, Panek AD (1997). "Trehalose accumulation in mutants of Saccharomyces cerevisiae deleted in the UDPG-dependent trehalose synthase-phosphatase complex." Biochim Biophys Acta 1997;1335(1-2);40-50. PMID: 9133641

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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