MetaCyc Enzyme: phosphatidylcholine:diacylglycerol cholinephosphotransferase

Gene: AT3G15820

Species: Arabidopsis thaliana col

Unification Links: PhylomeDB:Q9LVZ7 , Pride:Q9LVZ7 , Protein Model Portal:Q9LVZ7 , String:3702.AT3G15820.1-P , TAIR:At3G15820 , UniProt:Q9LVZ7

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Created 09-May-2011 by Zhang P , PMN

Enzymatic reaction of: phosphatidylcholine:diacylglycerol cholinephosphotransferase

EC Number: 2.7.8.-

a phosphatidylcholine + a 1,2-diacyl-sn-glycerol <=> a 1,2-diacyl-sn-glycerol + a phosphatidylcholine

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Reversibility of this reaction is unspecified.

In Pathways: diacylglycerol biosynthesis (PUFA enrichment in oilseed)

A novel enzyme was recently isolated from Arabidopsis [Lu09a]. The Arabidopsis phosphatidylcholine:diacylglycerol cholinephosphotransferase, encoded by ROD1, catalyzed the transfer of phosphocholine head group from PC to DAG. Yeast microsomes expressing ROD1 had an enzyme activity of 0.6 nmol/mg/min in the absence of added PC, whereas the enzyme activity increased to 4.5 nmol/mg/min when 1 mM PC was added.

pH(opt): 6.5-7 [Lu09a]


Lu09a: Lu C, Xin Z, Ren Z, Miquel M, Browse J (2009). "An enzyme regulating triacylglycerol composition is encoded by the ROD1 gene of Arabidopsis." Proc Natl Acad Sci U S A 106(44);18837-42. PMID: 19833868

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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