Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
twitter

MetaCyc Polypeptide: 30S ribosomal subunit protein S7

Gene: rpsG Accession Numbers: EG10906 (MetaCyc), b3341, ECK3328

Species: Escherichia coli K-12 substr. MG1655

Component of:
30S ribosomal subunit
ribosome

Summary:
The S7 protein is a component of the 30S subunit of the ribosome.

S7 binds to 16S rRNA [Ehresmann76, Wower83, Hajnsdorf86, Chiaruttini86, Wiener87, Wiener88, Urlaub95, Dragon93, Dragon94, Robert00]. The ability of both S4 and S7 to bind 16S rRNA by themselves indicates that they function as initiator proteins for the assembly of the 30S subunit of the ribosome. The S9, S13, S19, S10, S14, and S3 subunits depend on S7 for assembly [Nowotny88, Grondek04, Bunner10]. The K35 residue of S7 appears to be required for efficient assembly [Fredrick00].

S7 crosslinks to the anticodon loop of tRNAs, indicating its location close to the decoding site of the ribosome [Podkowinski89, Rosen97]. S7 also crosslinks to mRNA [Stade89, Dontsova91]; the C-terminal region of S7 is the predominant crosslinking site [Greuer99]. S7 was also shown to crosslink to IF3 [MacKeen80, Cooperman81, Boileau83]. Footprinting of IF3 on 16S rRNA and modelling of IF3-30S subunit interactions suggested that IF3 is located near S7 and S11 [Dallas01]. S7 and S11 functionally interact [Robert03]. In addition, S7 is the major crosslinking target of the 4.5S RNA component of the signal recognition particle [Gu05].

S7 is a translational feedback repressor [Dean81], regulating the synthesis of itself and the other gene products encoded together with S7 in an operon: S12, S7, EF-G and possibly EF-Tu [Saito94]. Independently expressed S7 is not subject to translational autoregulation; therefore, regulation of S7 is achieved through regulation of translation of S12 and translational coupling with S12 [Saito94]. Two regions located between rpsL and rpsG interact with S7 and are important for S7-mediated repression [Saito94a, Golovin06, Surdina08]. The same determinants of S7 that are responsible for binding 16S rRNA are also involved in binding to its own mRNA [Robert01].

The antibiotic puromycin can be crosslinked to an amino-terminal peptide of S7 [Bischof94]. A deletion that truncates the β-hairpin of S7, ΔR77-Y84, increases ribosomal frameshifting, indicating that the ribosomal E (exit) site plays a role in reading frame maintenance [Devaraj09].

Locations: cytosol, ribosome, membrane

Map Position: [3,471,564 <- 3,472,103]

Unification Links: ASAP:ABE-0010917 , CGSC:224 , DIP:DIP-10783N , EchoBASE:EB0899 , EcoGene:EG10906 , EcoliWiki:b3341 , Mint:MINT-1236482 , ModBase:P02359 , OU-Microarray:b3341 , PortEco:b3341 , PR:PRO_000023860 , Pride:P02359 , Protein Model Portal:P02359 , RefSeq:NP_417800 , RegulonDB:EG10906 , SMR:P02359 , String:511145.b3341 , UniProt:P02359

Relationship Links: InterPro:IN-FAMILY:IPR000235 , InterPro:IN-FAMILY:IPR005717 , InterPro:IN-FAMILY:IPR020606 , InterPro:IN-FAMILY:IPR023798 , Panther:IN-FAMILY:PTHR11205 , Panther:IN-FAMILY:PTHR11205:SF13 , PDB:Structure:1EG0 , PDB:Structure:1M5G , PDB:Structure:1ML5 , PDB:Structure:1P6G , PDB:Structure:1P87 , PDB:Structure:1VS5 , PDB:Structure:1VS7 , PDB:Structure:2AVY , PDB:Structure:2AW7 , PDB:Structure:2GY9 , PDB:Structure:2GYB , PDB:Structure:2I2P , PDB:Structure:2I2U , PDB:Structure:2QAL , PDB:Structure:2QAN , PDB:Structure:2QB9 , PDB:Structure:2QBB , PDB:Structure:2QBD , PDB:Structure:2QBF , PDB:Structure:2QBH , PDB:Structure:2QBJ , PDB:Structure:2QOU , PDB:Structure:2QOW , PDB:Structure:2QOY , PDB:Structure:2QP0 , PDB:Structure:2VHO , PDB:Structure:2VHP , PDB:Structure:2WWL , PDB:Structure:2YKR , PDB:Structure:2Z4K , PDB:Structure:2Z4M , PDB:Structure:3DF1 , PDB:Structure:3DF3 , PDB:Structure:3E1A , PDB:Structure:3E1C , PDB:Structure:3FIH , PDB:Structure:3I1M , PDB:Structure:3I1O , PDB:Structure:3I1Q , PDB:Structure:3I1S , PDB:Structure:3I1Z , PDB:Structure:3I21 , PDB:Structure:3IZV , PDB:Structure:3IZW , PDB:Structure:3J00 , PDB:Structure:3J0U , PDB:Structure:3J0V , PDB:Structure:3J0X , PDB:Structure:3J0Z , PDB:Structure:3J10 , PDB:Structure:3J13 , PDB:Structure:3J18 , PDB:Structure:3J36 , PDB:Structure:3KC4 , PDB:Structure:3OAQ , PDB:Structure:3OAR , PDB:Structure:3OFA , PDB:Structure:3OFB , PDB:Structure:3OFO , PDB:Structure:3OFP , PDB:Structure:3OFX , PDB:Structure:3OFY , PDB:Structure:3OR9 , PDB:Structure:3ORA , PDB:Structure:3SFS , PDB:Structure:3UOQ , PDB:Structure:4A2I , PDB:Structure:4ADV , PDB:Structure:4GAQ , PDB:Structure:4GAS , PDB:Structure:4GD1 , PDB:Structure:4GD2 , PDB:Structure:4KIY , PDB:Structure:4KJ0 , PDB:Structure:4KJ2 , PDB:Structure:4KJ4 , PDB:Structure:4KJ6 , PDB:Structure:4KJ8 , PDB:Structure:4KJA , PDB:Structure:4KJC , Pfam:IN-FAMILY:PF00177 , Prosite:IN-FAMILY:PS00052

Ortholog Links: Ecol199310Cyc (Escherichia coli CFT073):C4114 , EcoO157Cyc (Escherichia coli O157:H7 str. EDL933):RPSG , ShigellaCyc (Shigella flexneri 2a str. 2457T):RPSG

Gene-Reaction Schematic: ?

GO Terms:

Biological Process: GO:0000028 - ribosomal small subunit assembly Inferred from experiment [Nowotny88]
GO:0017148 - negative regulation of translation Inferred from experiment [Dean81]
GO:0006412 - translation Inferred by computational analysis [GOA06, GOA01a]
Molecular Function: GO:0003729 - mRNA binding Inferred from experiment [Saito94a, Golovin06]
GO:0005515 - protein binding Inferred from experiment [Rajagopala14, Lasserre06, Butland05, MartinezHackert09]
GO:0019843 - rRNA binding Inferred from experiment Inferred by computational analysis [UniProtGOA11a, GOA06, Wower83]
GO:0000049 - tRNA binding Inferred by computational analysis [UniProtGOA11a, GOA06]
GO:0003723 - RNA binding Inferred by computational analysis [UniProtGOA11a, GOA01a]
GO:0003735 - structural constituent of ribosome Inferred by computational analysis [GOA01a]
Cellular Component: GO:0005829 - cytosol Inferred from experiment Inferred by computational analysis [DiazMejia09, Ishihama08]
GO:0016020 - membrane Inferred from experiment [Lasserre06]
GO:0022627 - cytosolic small ribosomal subunit Inferred from experiment [Hindennach71a, Lasserre06]
GO:0005840 - ribosome Inferred by computational analysis [UniProtGOA11a]
GO:0015935 - small ribosomal subunit Inferred by computational analysis [GOA01a]
GO:0030529 - ribonucleoprotein complex Inferred by computational analysis [UniProtGOA11a]

MultiFun Terms: cell structure ribosomes
information transfer protein related ribosomal proteins
information transfer protein related translation

Credits:
Last-Curated ? 15-Mar-2006 by Keseler I , SRI International


Subunit of: 30S ribosomal subunit

Synonyms: ribosome, small subunit

Species: Escherichia coli K-12 substr. MG1655

Subunit composition of 30S ribosomal subunit = [RpsA][RpsB][RpsC][RpsD][RpsE][RpsF][RpsG][RpsH][RpsI][RpsJ][RpsK][RpsL][RpsM][RpsN][RpsO][RpsP][RpsQ][RpsR][RpsS][RpsT][RpsU][Sra][16S ribosomal RNA (rrsA)]
         30S ribosomal subunit protein S1 = RpsA (extended summary available)
         30S ribosomal subunit protein S2 = RpsB (summary available)
         30S ribosomal subunit protein S3 = RpsC (summary available)
         30S ribosomal subunit protein S4 = RpsD (extended summary available)
         30S ribosomal subunit protein S5 = RpsE (extended summary available)
         30S ribosomal subunit protein S6 = RpsF (extended summary available)
         30S ribosomal subunit protein S7 = RpsG (extended summary available)
         30S ribosomal subunit protein S8 = RpsH (extended summary available)
         30S ribosomal subunit protein S9 = RpsI (extended summary available)
         30S ribosomal subunit protein S10 = RpsJ (extended summary available)
         30S ribosomal subunit protein S11 = RpsK (summary available)
         30S ribosomal subunit protein S12 = RpsL (extended summary available)
         30S ribosomal subunit protein S13 = RpsM (extended summary available)
         30S ribosomal subunit protein S14 = RpsN (summary available)
         30S ribosomal subunit protein S15 = RpsO (extended summary available)
         30S ribosomal subunit protein S16 = RpsP (summary available)
         30S ribosomal subunit protein S17 = RpsQ (summary available)
         30S ribosomal subunit protein S18 = RpsR (extended summary available)
         30S ribosomal subunit protein S19 = RpsS (summary available)
         30S ribosomal subunit protein S20 = RpsT (extended summary available)
         30S ribosomal subunit protein S21 = RpsU (summary available)
         30S ribosomal subunit protein S22 = Sra (summary available)

Component of: ribosome

Enzymes activated by 30S ribosomal subunit, sorted by the type of activation, are:

Activator (Mechanism unknown) of: GTPase [Daigle04, Himeno04]

Credits:
Created 28-Mar-2006 by Keseler I , SRI International


Subunit of: ribosome

Species: Escherichia coli K-12 substr. MG1655

Subunit composition of ribosome = [(RpsA)(RpsB)(RpsC)(RpsD)(RpsE)(RpsF)(RpsG)(RpsH)(RpsI)(RpsJ)(RpsK)(RpsL)(RpsM)(RpsN)(RpsO)(RpsP)(RpsQ)(RpsR)(RpsS)(RpsT)(RpsU)(Sra)(16S ribosomal RNA (rrsA))][(RplA)(RplB)(RplC)(RplD)(RplE)(RplF)([RplJ][(RplL)2]2)(RplI)(RplJ)(RplK)(RplM)(RplN)(RplO)(RplP)(RplQ)(RplR)(RplS)(RplT)(RplU)(RplV)(RplW)(RplX)(RplY)(RpmA)(RpmB)(RpmC)(RpmD)(RpmE)(RpmF)(RpmG)(RpmH)(RpmI)(RpmJ)(5S ribosomal RNA (rrfA))(23S ribosomal RNA (rrlA))]
         30S ribosomal subunit = (RpsA)(RpsB)(RpsC)(RpsD)(RpsE)(RpsF)(RpsG)(RpsH)(RpsI)(RpsJ)(RpsK)(RpsL)(RpsM)(RpsN)(RpsO)(RpsP)(RpsQ)(RpsR)(RpsS)(RpsT)(RpsU)(Sra)(16S ribosomal RNA (rrsA))
                 30S ribosomal subunit protein S1 = RpsA (extended summary available)
                 30S ribosomal subunit protein S2 = RpsB (summary available)
                 30S ribosomal subunit protein S3 = RpsC (summary available)
                 30S ribosomal subunit protein S4 = RpsD (extended summary available)
                 30S ribosomal subunit protein S5 = RpsE (extended summary available)
                 30S ribosomal subunit protein S6 = RpsF (extended summary available)
                 30S ribosomal subunit protein S7 = RpsG (extended summary available)
                 30S ribosomal subunit protein S8 = RpsH (extended summary available)
                 30S ribosomal subunit protein S9 = RpsI (extended summary available)
                 30S ribosomal subunit protein S10 = RpsJ (extended summary available)
                 30S ribosomal subunit protein S11 = RpsK (summary available)
                 30S ribosomal subunit protein S12 = RpsL (extended summary available)
                 30S ribosomal subunit protein S13 = RpsM (extended summary available)
                 30S ribosomal subunit protein S14 = RpsN (summary available)
                 30S ribosomal subunit protein S15 = RpsO (extended summary available)
                 30S ribosomal subunit protein S16 = RpsP (summary available)
                 30S ribosomal subunit protein S17 = RpsQ (summary available)
                 30S ribosomal subunit protein S18 = RpsR (extended summary available)
                 30S ribosomal subunit protein S19 = RpsS (summary available)
                 30S ribosomal subunit protein S20 = RpsT (extended summary available)
                 30S ribosomal subunit protein S21 = RpsU (summary available)
                 30S ribosomal subunit protein S22 = Sra (summary available)
         50S ribosomal subunit = (RplA)(RplB)(RplC)(RplD)(RplE)(RplF)([RplJ][(RplL)2]2)(RplI)(RplJ)(RplK)(RplM)(RplN)(RplO)(RplP)(RplQ)(RplR)(RplS)(RplT)(RplU)(RplV)(RplW)(RplX)(RplY)(RpmA)(RpmB)(RpmC)(RpmD)(RpmE)(RpmF)(RpmG)(RpmH)(RpmI)(RpmJ)(5S ribosomal RNA (rrfA))(23S ribosomal RNA (rrlA))
                 50S ribosomal subunit protein L1 = RplA (extended summary available)
                 50S ribosomal subunit protein L2 = RplB (summary available)
                 50S ribosomal subunit protein L3 = RplC (summary available)
                 50S ribosomal subunit protein L4 = RplD (extended summary available)
                 50S ribosomal subunit protein L5 = RplE (summary available)
                 50S ribosomal subunit protein L6 = RplF (summary available)
                 50S ribosomal protein complex L8 = (RplJ)([RplL]2)2
                         50S ribosomal subunit protein L10 = RplJ (extended summary available)
                         50S ribosomal subunit protein L7/L12 dimer = (RplL)2
                                 50S ribosomal subunit protein L12 = RplL
                 50S ribosomal subunit protein L9 = RplI (summary available)
                 50S ribosomal subunit protein L10 = RplJ (extended summary available)
                 50S ribosomal subunit protein L11 = RplK (extended summary available)
                 50S ribosomal subunit protein L13 = RplM (extended summary available)
                 50S ribosomal subunit protein L14 = RplN (extended summary available)
                 50S ribosomal subunit protein L15 = RplO (summary available)
                 50S ribosomal subunit protein L16 = RplP (extended summary available)
                 50S ribosomal subunit protein L17 = RplQ (summary available)
                 50S ribosomal subunit protein L18 = RplR (extended summary available)
                 50S ribosomal subunit protein L19 = RplS (extended summary available)
                 50S ribosomal subunit protein L20 = RplT (extended summary available)
                 50S ribosomal subunit protein L21 = RplU (summary available)
                 50S ribosomal subunit protein L22 = RplV (extended summary available)
                 50S ribosomal subunit protein L23 = RplW (extended summary available)
                 50S ribosomal subunit protein L24 = RplX (summary available)
                 50S ribosomal subunit protein L25 = RplY (summary available)
                 50S ribosomal subunit protein L27 = RpmA (extended summary available)
                 50S ribosomal subunit protein L28 = RpmB (summary available)
                 50S ribosomal subunit protein L29 = RpmC (summary available)
                 50S ribosomal subunit protein L30 = RpmD (summary available)
                 50S ribosomal subunit protein L31 = RpmE (summary available)
                 50S ribosomal subunit protein L32 = RpmF (summary available)
                 50S ribosomal subunit protein L33 = RpmG (summary available)
                 50S ribosomal subunit protein L34 = RpmH (summary available)
                 50S ribosomal subunit protein L35 = RpmI (summary available)
                 50S ribosomal subunit protein L36 = RpmJ (summary available)

Credits:
Created 15-Jun-2006 by Keseler I , SRI International


Sequence Features

Feature Class Location Citations Comment
Cleavage-of-Initial-Methionine 1
[Reinbolt79, UniProt08]
UniProt: Removed;
Mutagenesis-Variant 2 -> 18
[Robert01, Fredrick00, UniProt11]
Alternate sequence: missing; UniProt: Defective in ribosome assembly; accumulates to abnormally high levels on polysomes; significantly decreases affinity for its own mRNA.
Chain 2 -> 179
[UniProt09]
UniProt: 30S ribosomal protein S7;
Mutagenesis-Variant 36
[Robert01, Fredrick00, UniProt11]
Alternate sequence: E; UniProt: Defective in ribosome assembly.
Alternate sequence: A; UniProt: Defective in ribosome assembly.
Sequence-Conflict 92
[Reinbolt79, UniProt10a]
Alternate sequence: missing; UniProt: (in Ref. 3; AA sequence);
Mutagenesis-Variant 116
[Robert01, Fredrick00, UniProt11]
Alternate sequence: G; UniProt: Significantly decreases affinity for its own mRNA.
Extrinsic-Sequence-Variant 157 -> 179
[UniProt10a]
Alternate sequence: missing; UniProt: (in strain: B and L44);

History:
10/20/97 Gene b3341 from Blattner lab Genbank (v. M52) entry merged into EcoCyc gene EG10906; confirmed by SwissProt match.


References

Bischof94: Bischof O, Kruft V, Wittmann-Liebold B (1994). "Analysis of the puromycin binding site in the 70 S ribosome of Escherichia coli at the peptide level." J Biol Chem 269(28);18315-9. PMID: 8034577

Boileau83: Boileau G, Butler P, Hershey JW, Traut RR (1983). "Direct cross-links between initiation factors 1, 2, and 3 and ribosomal proteins promoted by 2-iminothiolane." Biochemistry 22(13);3162-70. PMID: 6349681

Bunner10: Bunner AE, Beck AH, Williamson JR (2010). "Kinetic cooperativity in Escherichia coli 30S ribosomal subunit reconstitution reveals additional complexity in the assembly landscape." Proc Natl Acad Sci U S A 107(12);5417-22. PMID: 20207951

Butland05: Butland G, Peregrin-Alvarez JM, Li J, Yang W, Yang X, Canadien V, Starostine A, Richards D, Beattie B, Krogan N, Davey M, Parkinson J, Greenblatt J, Emili A (2005). "Interaction network containing conserved and essential protein complexes in Escherichia coli." Nature 433(7025);531-7. PMID: 15690043

Chiaruttini86: Chiaruttini C, Milet M, Hayes DH, Expert-Bezancon A (1986). "Multiple crosslinks of proteins S7 and S9 to domains 3 and 4 of 16S ribosomal RNA in the Escherichia coli 30S particle." Eur J Biochem 160(2);363-70. PMID: 2429836

Cooperman81: Cooperman BS, Expert-Bezancon A, Kahan L, Dondon J, Grunberg-Manago M (1981). "IF-3 crosslinking to Escherichia coli ribosomal 30 S subunits by three different light-dependent procedures: identification of 30 S proteins crosslinked to IF-3--utilization of a new two-stage crosslinking reagent, p-nitrobenzylmaleimide." Arch Biochem Biophys 208(2);554-62. PMID: 7020604

Daigle04: Daigle DM, Brown ED (2004). "Studies of the interaction of Escherichia coli YjeQ with the ribosome in vitro." J Bacteriol 186(5);1381-7. PMID: 14973029

Dallas01: Dallas A, Noller HF (2001). "Interaction of translation initiation factor 3 with the 30S ribosomal subunit." Mol Cell 8(4);855-64. PMID: 11684020

Dean81: Dean D, Yates JL, Nomura M (1981). "Identification of ribosomal protein S7 as a repressor of translation within the str operon of E. coli." Cell 24(2);413-9. PMID: 7016341

Devaraj09: Devaraj A, Shoji S, Holbrook ED, Fredrick K (2009). "A role for the 30S subunit E site in maintenance of the translational reading frame." RNA 15(2);255-65. PMID: 19095617

DiazMejia09: Diaz-Mejia JJ, Babu M, Emili A (2009). "Computational and experimental approaches to chart the Escherichia coli cell-envelope-associated proteome and interactome." FEMS Microbiol Rev 33(1);66-97. PMID: 19054114

Dontsova91: Dontsova O, Kopylov A, Brimacombe R (1991). "The location of mRNA in the ribosomal 30S initiation complex; site-directed cross-linking of mRNA analogues carrying several photo-reactive labels simultaneously on either side of the AUG start codon." EMBO J 10(9);2613-20. PMID: 1651232

Dragon93: Dragon F, Brakier-Gingras L (1993). "Interaction of Escherichia coli ribosomal protein S7 with 16S rRNA." Nucleic Acids Res 21(5);1199-203. PMID: 7681943

Dragon94: Dragon F, Payant C, Brakier-Gingras L (1994). "Mutational and structural analysis of the RNA binding site for Escherichia coli ribosomal protein S7." J Mol Biol 244(1);74-85. PMID: 7525976

Ehresmann76: Ehresmann B, Reinbolt J, Backendorf C, Tritsch D, Ebel J (1976). "Studies of the binding sites of Escherichia coli ribosomal protein S7 with 16S RNA by ultraviolet irradiation." FEBS Lett 67(3);316-9. PMID: 786727

Fredrick00: Fredrick K, Dunny GM, Noller HF (2000). "Tagging ribosomal protein S7 allows rapid identification of mutants defective in assembly and function of 30 S subunits." J Mol Biol 298(3);379-94. PMID: 10772857

GOA01a: GOA, DDB, FB, MGI, ZFIN (2001). "Gene Ontology annotation through association of InterPro records with GO terms."

GOA06: GOA, SIB (2006). "Electronic Gene Ontology annotations created by transferring manual GO annotations between orthologous microbial proteins."

Golovin06: Golovin A, Spiridonova V, Kopylov A (2006). "Mapping contacts of the S12-S7 intercistronic region of str operon mRNA with ribosomal protein S7 of E. coli." FEBS Lett 580(25);5858-62. PMID: 17027976

Greuer99: Greuer B, Thiede B, Brimacombe R (1999). "The cross-link from the upstream region of mRNA to ribosomal protein S7 is located in the C-terminal peptide: experimental verification of a prediction from modeling studies." RNA 5(12);1521-5. PMID: 10606263

Grondek04: Grondek JF, Culver GM (2004). "Assembly of the 30S ribosomal subunit: positioning ribosomal protein S13 in the S7 assembly branch." RNA 10(12);1861-6. PMID: 15525707

Gu05: Gu SQ, Jockel J, Beinker P, Warnecke J, Semenkov YP, Rodnina MV, Wintermeyer W (2005). "Conformation of 4.5S RNA in the signal recognition particle and on the 30S ribosomal subunit." RNA 11(9);1374-84. PMID: 16043501

Hajnsdorf86: Hajnsdorf E, Favre A, Expert-Bezancon A (1986). "Multiple crosslinks of proteins S7, S9, S13 to domains 3 and 4 of 16S RNA in the 30S particle." Nucleic Acids Res 14(10);4009-23. PMID: 2423965

Himeno04: Himeno H, Hanawa-Suetsugu K, Kimura T, Takagi K, Sugiyama W, Shirata S, Mikami T, Odagiri F, Osanai Y, Watanabe D, Goto S, Kalachnyuk L, Ushida C, Muto A (2004). "A novel GTPase activated by the small subunit of ribosome." Nucleic Acids Res 32(17);5303-9. PMID: 15466596

Hindennach71a: Hindennach I, Stoffler G, Wittmann HG (1971). "Ribosomal proteins. Isolation of the proteins from 30S ribosomal subunits of Escherichia coli." Eur J Biochem 23(1);7-11. PMID: 4942549

Ishihama08: Ishihama Y, Schmidt T, Rappsilber J, Mann M, Hartl FU, Kerner MJ, Frishman D (2008). "Protein abundance profiling of the Escherichia coli cytosol." BMC Genomics 9;102. PMID: 18304323

Lasserre06: Lasserre JP, Beyne E, Pyndiah S, Lapaillerie D, Claverol S, Bonneu M (2006). "A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis." Electrophoresis 27(16);3306-21. PMID: 16858726

MacKeen80: MacKeen LA, Kahan L, Wahba AJ, Schwartz I (1980). "Photochemical cross-linking of initiation factor-3 to Escherichia coli 30 S ribosomal subunits." J Biol Chem 255(21);10526-31. PMID: 7000779

MartinezHackert09: Martinez-Hackert E, Hendrickson WA (2009). "Promiscuous substrate recognition in folding and assembly activities of the trigger factor chaperone." Cell 138(5);923-34. PMID: 19737520

Nowotny88: Nowotny V, Nierhaus KH (1988). "Assembly of the 30S subunit from Escherichia coli ribosomes occurs via two assembly domains which are initiated by S4 and S7." Biochemistry 27(18);7051-5. PMID: 2461734

Podkowinski89: Podkowinski J, Gornicki P (1989). "Ribosomal proteins S7 and L1 are located close to the decoding site of E. coli ribosome--affinity labeling studies with modified tRNAs carrying photoreactive probes attached adjacent to the 3'-end of the anticodon." Nucleic Acids Res 17(21);8767-82. PMID: 2685749

Rajagopala14: Rajagopala SV, Sikorski P, Kumar A, Mosca R, Vlasblom J, Arnold R, Franca-Koh J, Pakala SB, Phanse S, Ceol A, Hauser R, Siszler G, Wuchty S, Emili A, Babu M, Aloy P, Pieper R, Uetz P (2014). "The binary protein-protein interaction landscape of Escherichia coli." Nat Biotechnol 32(3);285-90. PMID: 24561554

Reinbolt79: Reinbolt J, Tritsch D, Wittmann-Liebold B (1979). "The primary structure of ribosomal protein S7 from E. coli strains K and B." Biochimie 61(4);501-22. PMID: 385062

Robert00: Robert F, Gagnon M, Sans D, Michnick S, Brakier-Gingras L (2000). "Mapping of the RNA recognition site of Escherichia coli ribosomal protein S7." RNA 6(11);1649-59. PMID: 11105763

Robert01: Robert F, Brakier-Gingras L (2001). "Ribosomal protein S7 from Escherichia coli uses the same determinants to bind 16S ribosomal RNA and its messenger RNA." Nucleic Acids Res 29(3);677-82. PMID: 11160889

Robert03: Robert F, Brakier-Gingras L (2003). "A functional interaction between ribosomal proteins S7 and S11 within the bacterial ribosome." J Biol Chem 278(45);44913-20. PMID: 12937172

Rosen97: Rosen KV, Zimmerman RA (1997). "Photoaffinity labeling of 30S-subunit proteins S7 and S11 by 4-thiouridine-substituted tRNA(Phe) situated at the P site of Escherichia coli ribosomes." RNA 3(9);1028-36. PMID: 9292501

Saito94: Saito K, Mattheakis LC, Nomura M (1994). "Post-transcriptional regulation of the str operon in Escherichia coli. Ribosomal protein S7 inhibits coupled translation of S7 but not its independent translation." J Mol Biol 235(1);111-24. PMID: 7507167

Saito94a: Saito K, Nomura M (1994). "Post-transcriptional regulation of the str operon in Escherichia coli. Structural and mutational analysis of the target site for translational repressor S7." J Mol Biol 235(1);125-39. PMID: 8289236

Stade89: Stade K, Rinke-Appel J, Brimacombe R (1989). "Site-directed cross-linking of mRNA analogues to the Escherichia coli ribosome; identification of 30S ribosomal components that can be cross-linked to the mRNA at various points 5' with respect to the decoding site." Nucleic Acids Res 17(23);9889-908. PMID: 2690012

Surdina08: Surdina AV, Rassokhin TI, Golovin AV, Spiridonova VA, Kraal B, Kopylov AM (2008). "Selection of random RNA fragments as method for searching for a site of regulation of translation of E. coli streptomycin mRNA by ribosomal protein S7." Biochemistry (Mosc) 73(6);652-9. PMID: 18620530

UniProt08: UniProt Consortium (2008). "UniProt version 14.6 released on 2008-12-16." Database.

UniProt09: UniProt Consortium (2009). "UniProt version 15.8 released on 2009-10-01 00:00:00." Database.

UniProt10a: UniProt Consortium (2010). "UniProt version 2010-11 released on 2010-11-02 00:00:00." Database.

UniProt11: UniProt Consortium (2011). "UniProt version 2011-06 released on 2011-06-30 00:00:00." Database.

UniProtGOA11a: UniProt-GOA (2011). "Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries."

Urlaub95: Urlaub H, Kruft V, Bischof O, Muller EC, Wittmann-Liebold B (1995). "Protein-rRNA binding features and their structural and functional implications in ribosomes as determined by cross-linking studies." EMBO J 14(18);4578-88. PMID: 7556101

Wiener87: Wiener L, Brimacombe R (1987). "Protein binding sites on Escherichia coli 16S RNA; RNA regions that are protected by proteins S7, S14 and S19 in the presence or absence of protein S9." Nucleic Acids Res 15(9);3653-70. PMID: 2438658

Wiener88: Wiener L, Schuler D, Brimacombe R (1988). "Protein binding sites on Escherichia coli 16S ribosomal RNA; RNA regions that are protected by proteins S7, S9 and S19, and by proteins S8, S15 and S17." Nucleic Acids Res 16(4);1233-50. PMID: 3279390

Wower83: Wower I, Brimacombe R (1983). "The localization of multiple sites on 16S RNA which are cross-linked to proteins S7 and S8 in Escherichia coli 30S ribosomal subunits by treatment with 2-iminothiolane." Nucleic Acids Res 11(5);1419-37. PMID: 6338481


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Wed Dec 17, 2014, BIOCYC14B.