MetaCyc Enzyme: beta-caryophyllene synthase

Gene: bcp Accession Number: G-11363 (MetaCyc)

Synonyms: beta-caryophyllene synthase

Species: Cucumis sativus

A cDNA was isolated from leaves of cucumis plants that had been exposed to spider mite infection and treatment with jasmonic acid to induce sesquiterpenoid production. The cDNA was functionally expressed in E.coli and shown to be a terepen synthase. This enzyme catalyzed the conversion of FPP into beta-caryophyllene [Mercke04].

Molecular Weight of Polypeptide: 63.3 kD (from nucleotide sequence), 63.3 kD (experimental) [Mercke04 ]

Unification Links: Entrez-Nucleotide:AY640155 , Entrez:AAU05952 , Protein Model Portal:Q66PX8 , UniProt:Q66PX8

Relationship Links: InterPro:IN-FAMILY:IPR001906 , InterPro:IN-FAMILY:IPR005630 , InterPro:IN-FAMILY:IPR008930 , InterPro:IN-FAMILY:IPR008949 , Pfam:IN-FAMILY:PF01397 , Pfam:IN-FAMILY:PF03936

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Created 15-Jun-2009 by Pujar A , Boyce Thompson Institute

Enzymatic reaction of: beta-caryophyllene synthase

EC Number:

(2E,6E)-farnesyl diphosphate <=> (-)-β-caryophyllene + diphosphate

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is physiologically favored in the direction shown.

In Pathways: β-caryophyllene biosynthesis


Mercke04: Mercke P, Kappers IF, Verstappen FW, Vorst O, Dicke M, Bouwmeester HJ (2004). "Combined transcript and metabolite analysis reveals genes involved in spider mite induced volatile formation in cucumber plants." Plant Physiol 135(4);2012-24. PMID: 15310834

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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