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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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MetaCyc Enzyme: 3-oxoacyl-CoA hydrolase

Gene: MKS2 Accession Number: G-12179 (MetaCyc)

Synonyms: methylketone synthase IIc, methylketone synthase

Species: Solanum lycopersicum

Summary:
A cDNA clone was isolated from tomato, the cDNA was recombinantly expressed in E.coli and the protein functionally characterized. The gene encodes a plastid localized protein which acts as a thioesterase hydrolyzing 3-ketoacyl-ACP's releasing 3-ketoacids [Yu10].

Unification Links: Entrez-Nucleotide:GU987114 , Entrez:ADK38543

Gene-Reaction Schematic: ?

Instance reaction of [a 3-oxoacyl-CoA + H2O → a 3-oxoacid + coenzyme A + H+] (3.1.2.-):
i1: 3-oxo-myristoyl-CoA + H2O → 3-oxo-myristate + coenzyme A + H+ (3.1.2.-)

Credits:
Created 16-Sep-2010 by Pujar A , Boyce Thompson Institute


Enzymatic reaction of: 3-oxo-myristoyl-ACP hydrolase (3-oxoacyl-CoA hydrolase)

EC Number: 3.1.2.-

a 3-oxo-myristoyl-[acp] + H2O <=> 3-oxo-myristate + a holo-[acyl-carrier protein] + H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is favored in the direction shown.

In Pathways: 2-methylketone biosynthesis


Enzymatic reaction of: 3-oxoacyl-CoA hydrolase

EC Number: 3.1.2.-

a 3-oxoacyl-CoA + H2O <=> a 3-oxoacid + coenzyme A + H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is physiologically favored in the direction shown.

In Pathways: methyl ketone biosynthesis


Enzymatic reaction of: 3-oxo-myristoyl-CoA hydrolase (3-oxoacyl-CoA hydrolase)

EC Number: 3.1.2.-

3-oxo-myristoyl-CoA + H2O <=> 3-oxo-myristate + coenzyme A + H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is physiologically favored in the direction shown.


References

Yu10: Yu G, Nguyen TT, Guo Y, Schauvinhold I, Auldridge ME, Bhuiyan N, Ben-Israel I, Iijima Y, Fridman E, Noel JP, Pichersky E (2010). "Enzymatic functions of wild tomato methylketone synthases 1 and 2." Plant Physiol 154(1);67-77. PMID: 20605911


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 20, 2014, biocyc14.