Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
twitter

MetaCyc Enzyme: myo-inositol 4-O-methyltransferase

Gene: imt1 Accession Number: G-12581 (MetaCyc)

Species: Mesembryanthemum crystallinum

Summary:
A myo-inositol O-methyltransferase gene was cloned from the common ice plant, Mesembryanthemum crystallinum. Expression of the gene in leaves was found induced 4-5 times under salt-stress conditions. Assay of the recombinant protein clearly showed that ononitol was the formed product from myo-inositol [Vernon92]. It demonstrated that ononitol but not sequoyitol is the intermediate in pinitol biosynthesis in common ice plant.

Molecular Weight of Polypeptide: 40.0 kD (experimental) [Vernon92 ]

Unification Links: Protein Model Portal:P45986 , SMR:P45986 , UniProt:P45986

Relationship Links: InterPro:IN-FAMILY:IPR001077 , InterPro:IN-FAMILY:IPR011991 , InterPro:IN-FAMILY:IPR012967 , InterPro:IN-FAMILY:IPR016461 , Pfam:IN-FAMILY:PF00891 , Pfam:IN-FAMILY:PF08100 , Prosite:IN-FAMILY:PS51683

Gene-Reaction Schematic: ?

Credits:
Created 02-Mar-2011 by Zhang P , TAIR


Enzymatic reaction of: myo-inositol 4-O-methyltransferase

EC Number: 2.1.1.129

S-adenosyl-L-methionine + myo-inositol <=> S-adenosyl-L-homocysteine + D-ononitol + H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

The reaction is physiologically favored in the direction shown.

In Pathways: pinitol biosynthesis I


References

Vernon92: Vernon DM, Bohnert HJ (1992). "A novel methyl transferase induced by osmotic stress in the facultative halophyte Mesembryanthemum crystallinum." EMBO J 11(6);2077-85. PMID: 1600940


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Dec 19, 2014, BIOCYC14A.