|Gene:||CesA1||Accession Number: G-1681 (MetaCyc)|
Synonyms: At4g32410, rsw1, β-1,4-glucan synthase
Species: Arabidopsis thaliana col
Cellulose, the most abundant polysaccharide on earth, determines the orientation of cell expansion and provides supporting material for plant cells [Pauly08]. The cellulose-formed microfibrils, consisting of a linear chain of several hundred to over 10,000 β-1, 4-linked glucan, are synthesized by a plasma membrane-localized cellulose synthase complex (CSC). In vascular plants, multiple cellulose synthase catalytic subunits are required for cellulose synthesis [Taylor03]. The complex extrudes up to 36 individual cellulose chains that are bound together to form the cellulose microfibril [Wightman10]. Transgenic plants expressing antisense cellulose synthase constructs have reduced cellulose content.
Relationship Links: CAZy:IN-FAMILY:GT2 , InterPro:IN-FAMILY:IPR001841 , InterPro:IN-FAMILY:IPR005150 , InterPro:IN-FAMILY:IPR013083 , InterPro:IN-FAMILY:IPR027934 , Pfam:IN-FAMILY:PF03552 , Pfam:IN-FAMILY:PF14569 , Prosite:IN-FAMILY:PS00518 , Prosite:IN-FAMILY:PS50089 , Smart:IN-FAMILY:SM00184
Revised 30-Sep-2011 by Weerasinghe D
Enzymatic reaction of: UDP-glucose:1,4-β-D-glucan 4-β-D-glucosyltransferase (cellulose synthase)
EC Number: 220.127.116.11
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Reversibility of this reaction is unspecified.
In Pathways: cellulose biosynthesis
Burn02: Burn JE, Hocart CH, Birch RJ, Cork AC, Williamson RE (2002). "Functional analysis of the cellulose synthase genes CesA1, CesA2, and CesA3 in Arabidopsis." Plant Physiol 129(2);797-807. PMID: 12068120
Taylor03: Taylor NG, Howells RM, Huttly AK, Vickers K, Turner SR (2003). "Interactions among three distinct CesA proteins essential for cellulose synthesis." Proc Natl Acad Sci U S A 100(3);1450-5. PMID: 12538856
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