Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Enzyme: L-serine dehydratase

Gene: sdaA Accession Number: G-6543 (MetaCyc)

Species: Corynebacterium sp.

Summary:
The sdaA gene of Corynebacterium glutamicum, encoding an L-serine dehydratase (L-SerDH), was identified by sequence homology search, using the Escherichia coli sdaA, sdaB and tdcG sequences. The gene was cloned into a plasmid, and transformed back into C. glutamicum. The overexpressing strain demonstrated high activity of L-serDH, and was able to grow with L-serine as a single substrate, confirming the identity of the gene [Netzer04].

Unification Links: Entrez-gene:3343561 , ModBase:Q8NQ09 , Protein Model Portal:Q8NQ09 , String:196627.cg1852 , Swiss-Model:Q8NQ09 , UniProt:Q8NQ09

Relationship Links: InterPro:IN-FAMILY:IPR004644 , InterPro:IN-FAMILY:IPR005130 , InterPro:IN-FAMILY:IPR005131 , Pfam:IN-FAMILY:PF03313 , Pfam:IN-FAMILY:PF03315

Gene-Reaction Schematic: ?

MultiFun Terms: metabolism degradation of macromolecules proteins/peptides/glycopeptides


Enzymatic reaction of: L-serine dehydratase

L-serine <=> 2-aminoprop-2-enoate + H+ + H2O

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is favored in the direction shown.

In Pathways: glycine betaine degradation I


References

Netzer04: Netzer R, Peters-Wendisch P, Eggeling L, Sahm H (2004). "Cometabolism of a nongrowth substrate: L-serine utilization by Corynebacterium glutamicum." Appl Environ Microbiol 70(12);7148-55. PMID: 15574911


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Nov 22, 2014, biocyc13.