|Gene:||hemE||Accession Number: G-9033 (MetaCyc)|
Species: Rhodobacter sphaeroides
The molecular weight was determined by SDS-PAGE. The native molecular weight was 39 kD by gel filtration chromatography [Jones93a].
|Map Position: [2,424,282 -> 2,425,313]|
Molecular Weight of Polypeptide: 41 kD (experimental) [Jones93a ]
pI: 4.4 [Jones93a]
Enzymatic reaction of: uroporphyrinogen decarboxylase
EC Number: 188.8.131.52
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
The reaction is favored in the direction shown.
The enzyme was subject to substrate inhibition [Jones93a].
Inhibitors (Unknown Mechanism): porphobilinogen [Jones93a] , uroporphyrin I [Jones93a] , uroporphyrin III [Jones93a] , coproporphyrin I [Jones93a] , coproporphyrin III [Jones93a] , haematoporphyrin IX [Jones93a] , iodoacetamide [Jones93a] , N-ethylmaleimide [Jones93a] , phenylglyoxal [Jones93a] , Hg2+ [Jones93a] , Cu2+ [Jones93a]
pH(opt): 6.7-6.9 [Jones93a]
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