Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Enzyme: Dipeptidase 2 / LTD4 dipeptidase 2

Gene: DPEP2 Accession Number: HS09532 (MetaCyc)

Synonyms: UNQ284/PRO323

Species: Homo sapiens

Subunit composition of Dipeptidase 2 / LTD4 dipeptidase 2 = [DPEP2]2
         Dipeptidase 2 = DPEP2

Map Position: [68,399,040 <- 68,412,217]

Unification Links: ArrayExpress:Q9H4A9 , Ensembl:ENSG00000167261 , Entrez-gene:64174 , Entrez-Nucleotide:AJ295149 , Entrez-Nucleotide:AK092884 , Entrez-Nucleotide:BC024021 , Entrez:AAH24021 , Entrez:CAC14667 , GeneCards:LOC64174 , PhylomeDB:Q9H4A9 , Pride:Q9H4A9 , Protein Model Portal:Q9H4A9 , RefSeq:NM_022355 , RefSeq:NP_071750 , SMR:Q9H4A9 , String:9606.ENSP00000268795 , UCSC Human Genome:NM_022355 , UniGene:115537 , UniProt:Q9H4A9

Relationship Links: InterPro:IN-FAMILY:IPR000180 , InterPro:IN-FAMILY:IPR008257 , Panther:IN-FAMILY:PTHR10443 , Pfam:IN-FAMILY:PF01244 , Prosite:IN-FAMILY:PS00869 , Prosite:IN-FAMILY:PS51365

Gene-Reaction Schematic: ?

Instance reaction of [a dipeptide + H2O → 2 amino acids] (3.4.13.19):
i1: L-glutamyl-L-glutamate + H2O → 2 L-glutamate (3.4.13.7)

GO Terms:

Biological Process: GO:0006508 - proteolysis
Molecular Function: GO:0008239 - dipeptidyl-peptidase activity

Credits:
Created 26-Jun-2010 by Trupp M , SRI International


Enzymatic reaction of: Dipeptidase 2

EC Number: 3.4.13.19

a dipeptide + H2O <=> 2 amino acids

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

The reaction is physiologically favored in the direction shown.


Enzymatic reaction of: LTD4 dipeptidase 2

EC Number: 3.4.13.19

leukotriene-D4 + H2O <=> glycine + leukotriene-E4

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

The reaction is physiologically favored in the direction shown.

In Pathways: leukotriene biosynthesis

Exons/Introns:


References

Habib03: Habib GM, Shi ZZ, Cuevas AA, Lieberman MW (2003). "Identification of two additional members of the membrane-bound dipeptidase family." FASEB J 17(10);1313-5. PMID: 12738806


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, BIOCYC14A.