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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Enzyme: dihydroxyacetone kinase

Gene: dhaK Accession Number: G-3542 (MetaCyc)

Species: Citrobacter freundii

Subunit composition of dihydroxyacetone kinase = [DhaK]2
         dihydroxyacetone kinase subunit = DhaK

Molecular Weight of Polypeptide: 57 kD (experimental) [Daniel95 ]

Molecular Weight of Multimer: 105 kD (experimental) [Daniel95]

Unification Links: ModBase:P45510 , Protein Model Portal:P45510 , SMR:P45510 , Swiss-Model:P45510 , UniProt:P45510

Relationship Links: Entrez-Nucleotide:RELATED-TO:U09771 , InterPro:IN-FAMILY:IPR004006 , InterPro:IN-FAMILY:IPR004007 , InterPro:IN-FAMILY:IPR012734 , PDB:Structure:1UN8 , PDB:Structure:1UN9 , Pfam:IN-FAMILY:PF02733 , Pfam:IN-FAMILY:PF02734 , Prosite:IN-FAMILY:PS51480 , Prosite:IN-FAMILY:PS51481

Gene-Reaction Schematic: ?

MultiFun Terms: metabolism central intermediary metabolism misc. glycerol metabolism


Enzymatic reaction of: dihydroxyacetone kinase

EC Number: 2.7.1.29

dihydroxyacetone + ATP <=> dihydroxyacetone phosphate + ADP + H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction of enzyme catalysis.

The reaction is irreversible in the direction shown.

In Pathways: superpathway of glycerol degradation to 1,3-propanediol , glycerol degradation II

Activators (Allosteric): Mg2+ [Daniel95] , Ca2+ [Daniel95]

Kinetic Parameters:

Substrate
Km (μM)
Citations
dihydroxyacetone
30.0
[Daniel95]
ATP
70.0
[Daniel95]


References

Daniel95: Daniel R, Stuertz K, Gottschalk G (1995). "Biochemical and molecular characterization of the oxidative branch of glycerol utilization by Citrobacter freundii." J Bacteriol 177(15);4392-401. PMID: 7635824


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Dec 21, 2014, BIOCYC14A.