This view shows enzymes only for those organisms listed below, in the list of taxa known to possess the pathway. If an enzyme name is shown in bold, there is experimental evidence for this enzymatic activity.
Synonyms: orcinol metabolism
|Superclasses:||Degradation/Utilization/Assimilation → Aromatic Compounds Degradation|
Orcinol is a natural phenolic organic compound that occurs in many species of lichens, such as Roccella tinctoria. It is also a precursor of the phenolic methyl ether 3,5-dimethoxytoluene, the major scent compound of many rose varieties [Scalliet06]. Orcinol is also used in the production of the reddish-brown dye orcein and as a reagent in some chemical tests for pentoses, such as Bial's Test.
1,3-dihydroxy-derivatives of benzenoid are widespread products of plant and microbial metabolism [Chapman76]. 2,3,5-trihydroxytoluene can be rapidly and nonenzymatically oxidized to a quinone [Ohta75].
Unification Links: Eawag-BBD-Pathways:orc
Chapman76a: Chapman PJ, Ribbons DW (1976). "Metabolism of resorcinylic compounds by bacteria: alternative pathways for resorcinol catabolism in Pseudomonas putida." J Bacteriol 1976;125(3);985-98. PMID: 942589
Ohta75: Ohta Y, Higgins I, Ribbons DW (1975). "Metabolism of resorcinylic compounds by bacteria. Purification and properties of orcinol hydroxylase from Pseudomonas putida 01." J Biol Chem 1975;250(10);3814-25. PMID: 1126936
Ohta76: Ohta Y, Ribbons DW (1976). "Bacterial metabolism of resorcinylic compounds: purification and properties of orcinol hydroxylase and resorcinol hydroxylase from Pseudomonas putida ORC." Eur J Biochem 1976;61(1);259-69. PMID: 1280
Scalliet06: Scalliet G, Lionnet C, Le Bechec M, Dutron L, Magnard JL, Baudino S, Bergougnoux V, Jullien F, Chambrier P, Vergne P, Dumas C, Cock JM, Hugueney P (2006). "Role of petal-specific orcinol O-methyltransferases in the evolution of rose scent." Plant Physiol 140(1);18-29. PMID: 16361520
Davey75: Davey JF, Ribbons DW (1975). "Metabolism of resorcinylic compounds by bacteria. Purification and properties of acetylpyruvate hydrolase from Pseudomonas putida 01." J Biol Chem 1975;250(10);3826-30. PMID: 236305
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