This view shows enzymes only for those organisms listed below, in the list of taxa known to possess the pathway. If an enzyme name is shown in bold, there is experimental evidence for this enzymatic activity.
Synonyms: IAA biosynthesis from amide-conjugates, IAA deconjugation, indole-3-acetic acid biosynthesis from amide-conjugates, IAA activation I
|Superclasses:||Activation/Inactivation/Interconversion → Activation|
|Biosynthesis → Hormones Biosynthesis → Plant Hormones Biosynthesis → Auxins Biosynthesis|
Some taxa known to possess this pathway include : Arabidopsis thaliana col
Expected Taxonomic Range: Viridiplantae
The phytohormone family of auxins regulates many plant biological processes including cell division, elongation, differentiation, root initiation, tropic responses, flowering, fruit ripening, and senescence [Woodward05]. Indole-3-acetic acid (IAA) is the most abundant natural plant auxin.
In addition to de novo synthesis, IAA can be released from its conjugates. In Arabidopsis, the naturally occurring IAA amide conjugates indole-3-acetyl-leucine and indole-3-acetyl-alanine have been reported to be hydrolyzed to release free IAA [Bartel01, Kowalczyk].
Variants: indole-3-acetate activation II , indole-3-acetate biosynthesis I , indole-3-acetate biosynthesis II , indole-3-acetate biosynthesis III (bacteria) , indole-3-acetate biosynthesis IV (bacteria) , indole-3-acetate biosynthesis V (bacteria and fungi) , methyl indole-3-acetate interconversion , tryptophan degradation VII (via indole-3-pyruvate)
Unification Links: AraCyc:PWY-1822
Bartel01: Bartel, Bonnie, LeClere, Sherry, Magidin, Monica, Zolman, Bethany "Inputs to the active indole-3-acetic acid pool: de novo synthesis, conjugate hydrolysis, and indole-3-butyric acid beta-oxidation." Journal of Plant Growth Regulation (2001) 20:198-216.
Kowalczyk: Kowalczyk, Mariusz "Metabolism and homeostasis of indole-3-acetic acid in Arabidopsis thaliana." Doctoral diss. Dept. of Forest Genetics and Plant Physiol., SLU. Acta Universitatis Agriculturae Sueciae. Silvestria Vol. 256.
LeClere02: LeClere S, Tellez R, Rampey RA, Matsuda SP, Bartel B (2002). "Characterization of a family of IAA-amino acid conjugate hydrolases from Arabidopsis." J Biol Chem 277(23);20446-52. PMID: 11923288
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