This view shows enzymes only for those organisms listed below, in the list of taxa known to possess the pathway. If an enzyme name is shown in bold, there is experimental evidence for this enzymatic activity.
Synonyms: β-alanine biosynthesis from polyamines
|Superclasses:||Biosynthesis → Amino Acids Biosynthesis → Individual Amino Acids Biosynthesis → beta Alanine Biosynthesis|
Expected Taxonomic Range: Viridiplantae
β-Alanine is a central component of pantothenate biosynthesis. In bacteria the synthesis of β-alanine occurs through the decarboxylation of L-aspartate (see β-alanine biosynthesis III). This route of biosynthesis however appears to be unique to prokaryotes and absent in eukaryotes. In several plants species as well as yeast β-alanine was shown to be derived from the degradation of polyamines such as spermine and spermidine. Radiotracer experiments in Zea mays showed that maize shoots can convert spermidine and spermine to β-alanine and its biosynthesis intermediate 1,3-diaminopropane [Terano78]. Similarly fruit pericarp discs of tomato (Solanum lycopersicum) were shown to catabolize radiolabeled spermidine to putrescine and β-alanine [Rastogi89].
Unification Links: AraCyc:PWY-3981
Tanaka01a: Tanaka K, Matsuno E, Shimizu E, Shibai H, Yorifuji T (2001). "Purification and characterization of aminopropionaldehyde dehydrogenase from Arthrobacter sp. TMP-1." FEMS Microbiol Lett 195(2);191-6. PMID: 11179651
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