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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Pathway: superpathway of flavones and derivatives biosynthesis

If an enzyme name is shown in bold, there is experimental evidence for this enzymatic activity.

Superclasses: Superpathways

Some taxa known to possess this pathway include ? : Arabidopsis thaliana col , Catharanthus roseus , Chrysosplenium americanum , Eustoma exaltatum russellianum , Flaveria bidentis , Flaveria chlorifolia , Medicago sativa , Petunia x hybrida , Pisum sativum , Pueraria montana lobata , Sesbania rostrata , Vigna radiata radiata

Expected Taxonomic Range: Viridiplantae

Subpathways: rutin biosynthesis , quercetin glycoside biosynthesis (Arabidopsis) , methylquercetin biosynthesis , quercetin sulfate biosynthesis , kaempferol glycoside biosynthesis (Arabidopsis) , kaempferol triglucoside biosynthesis , syringetin biosynthesis , flavonol biosynthesis

Unification Links: PlantCyc:PWY-6266

Credits:
Created 03-Jun-2009 by Karthikeyan AS , TAIR

References Related to Enzymes, Genes, Subpathways, and Substrates of this Pathway

Ananvoranich94: Ananvoranich S, Varin L, Gulick P, Ibrahim R (1994). "Cloning and regulation of flavonol 3-sulfotransferase in cell-suspension cultures of Flaveria bidentis." Plant Physiol 106(2);485-91. PMID: 7991681

Barber62: Barber GA (1962). "Enzymic glycosylation of quercetin to rutin." Biochemistry 1;463-8. PMID: 13864833

Barber63: Barber GA (1963). "The formation of uridine diphosphate L-rhamnose by enzymes of the tobacco leaf." Arch Biochem Biophys 103;276-82. PMID: 14084592

Barber91: Barber GA, Behrman EJ (1991). "The synthesis and characterization of uridine 5'-(β-L-rhamnopyranosyl diphosphate) and its role in the enzymic synthesis of rutin." Arch Biochem Biophys 288(1);239-42. PMID: 1898019

Barron88: Barron, D, Varin, L, Ibrahim, R.K, Harborne, J.B, Williams C.A. (1988). "Sulphated flavonoids." Phytochemistry 27: 2375-2395.

Bredebach11: Bredebach M, Matern U, Martens S (2011). "Three 2-oxoglutarate-dependent dioxygenase activities of Equisetum arvense L. forming flavone and flavonol from (2S)-naringenin." Phytochemistry 72(7);557-63. PMID: 21353683

Brugliera99: Brugliera F, Barri-Rewell G, Holton TA, Mason JG (1999). "Isolation and characterization of a flavonoid 3'-hydroxylase cDNA clone corresponding to the Ht1 locus of Petunia hybrida." Plant J 19(4);441-51. PMID: 10504566

Buttery87: Buttery BR, Buzzell RI (1987). "Leaf Traits Associated with Flavonol Glycoside Genes in Soybean." Plant Physiol 85(1);20-21. PMID: 16665658

Cacace03: Cacace S, Schroder G, Wehinger E, Strack D, Schmidt J, Schroder J (2003). "A flavonol O-methyltransferase from Catharanthus roseus performing two sequential methylations." Phytochemistry 62(2);127-37. PMID: 12482447

Cosio84: Cosio EG, McClure JW (1984). "Kaempferol Glycosides and Enzymes of Flavonol Biosynthesis in Leaves of a Soybean Strain with Low Photosynthetic Rates." Plant Physiol 74(4);877-881. PMID: 16663526

Cristina11: Cristina Marcarini J, Ferreira Tsuboy MS, Cabral Luiz R, Regina Ribeiro L, Beatriz Hoffmann-Campo C, Segio Mantovani M (2011). "Investigation of cytotoxic, apoptosis-inducing, genotoxic and protective effects of the flavonoid rutin in HTC hepatic cells." Exp Toxicol Pathol 63(5);459-65. PMID: 20399630

De82: De Luca, V, Ibrahim, RG (1982). "Characterization of three distinct flavonol O-methyltransferases from Chrysosplenium americanum." Phytochemistry 21 1537-1540.

De85: De Luca V, Ibrahim RK (1985). "Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4'-O-methyltransferases." Arch Biochem Biophys 238(2);596-605. PMID: 3994393

De85a: De Luca V, Ibrahim RK (1985). "Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. II. Substrate interaction and product inhibition studies of flavonol 3-, 6-, and 4'-O-methyltransferases." Arch Biochem Biophys 238(2);606-18. PMID: 3994394

Fujita06: Fujita A, Goto-Yamamoto N, Aramaki I, Hashizume K (2006). "Organ-specific transcription of putative flavonol synthase genes of grapevine and effects of plant hormones and shading on flavonol biosynthesis in grape berry skins." Biosci Biotechnol Biochem 70(3);632-8. PMID: 16556978

FukuchiMitzutan11: Fukuchi-Mitzutani M, Akagi M, Ishiguro K, Katsmoto Y, Fukui Y, Togami J (2011). "Biochemical and molecular characterization of anthocyanidin/flavonol 3-glucosylation pathways in Rosa x hybrida." Plant Biotechnology 28: 239-244.

Furuya65: Furuya M, Galston AW (1965). "Flavonoid complexes in Pisum sativum L.- I Nature and distribution of the maior components." Phytochemistry, 4, 285-296.

Gachon05: Gachon CM, Langlois-Meurinne M, Saindrenan P (2005). "Plant secondary metabolism glycosyltransferases: the emerging functional analysis." Trends Plant Sci 10(11);542-9. PMID: 16214386

Gauthier98: Gauthier A, Gulick PJ, Ibrahim RK (1998). "Characterization of two cDNA clones which encode O-methyltransferases for the methylation of both flavonoid and phenylpropanoid compounds." Arch Biochem Biophys 351(2);243-9. PMID: 9514654

Gene96: Gene RM, Cartana C, Adzet T, Marin E, Parella T, Canigueral S (1996). "Anti-inflammatory and analgesic activity of Baccharis trimera: identification of its active constituents." Planta Med 62(3);232-5. PMID: 8693035

Showing only 20 references. To show more, press the button "Show all references".


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Mon Dec 22, 2014, biocyc12.