This view shows enzymes only for those organisms listed below, in the list of taxa known to possess the pathway. If an enzyme name is shown in bold, there is experimental evidence for this enzymatic activity.
|Superclasses:||Biosynthesis → Fatty Acid and Lipid Biosynthesis → Fatty Acid Biosynthesis → Unusual Fatty Acid Biosynthesis|
Some taxa known to possess this pathway include : Petunia x hybrida
Expected Taxonomic Range: Viridiplantae
Plant membranes have a large component of fatty acids, which help in controlling the permeability of the membrane to solutes moving in and out of cells. A number of cytochrome P450 enzymes participate in fatty acid biosynthesis. Similar to mammalian fatty acid biosynthetic enzymes, plants also posses ω-fatty acid hydroxylases. In A. thaliana, a ω-fatty acid hydroxylase which catalyzes the ω-hydroxylation of saturated and unsaturated fatty acids [Hofer08] has been studied.
Omega fatty acids are postulated to play major roles in plant development and plant defense. In Petunia x hybrida the characterization of diverse fatty acids in the flower development stages and the enzymes catalyzing them indicate a significant role in stigma-pollen recognition [Imaishi99]. Hydroxylated fatty acids are components of cutin and suberin and play a protective role by deflecting microbial attack.
Hofer08: Hofer R, Briesen I, Beck M, Pinot F, Schreiber L, Franke R (2008). "The Arabidopsis cytochrome P450 CYP86A1 encodes a fatty acid omega-hydroxylase involved in suberin monomer biosynthesis." J Exp Bot 59(9);2347-60. PMID: 18544608
Imaishi07: Imaishi H, Petkova-Andonova M (2007). "Molecular cloning of CYP76B9, a cytochrome P450 from Petunia hybrida, catalyzing the omega-hydroxylation of capric acid and lauric acid." Biosci Biotechnol Biochem 71(1);104-13. PMID: 17213671
Imaishi99: Imaishi H, Matsumoto Y, Ishitobi U, Ohkawa H (1999). "Encoding of a cytochrome P450-dependent lauric acid monooxygenase by CYP703A1 specifically expressed in the floral buds of petunia hybrida." Biosci Biotechnol Biochem 63(12);2082-90. PMID: 10664841
Benveniste82: Benveniste I, Salaun JP, Simon A, Reichhart D, Durst F (1982). "Cytochrome P-450-Dependent omega-Hydroxylation of Lauric Acid by Microsomes from Pea Seedlings." Plant Physiol 70(1);122-126. PMID: 16662431
Hunt06: Hunt MC, Rautanen A, Westin MA, Svensson LT, Alexson SE (2006). "Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs." FASEB J 20(11);1855-64. PMID: 16940157
Isbell06: Isbell, T.A, Lowery, B.A, DeKeyser, S.S, Winchell, A.L, Cermak, S.C (2006). "Physical properties of triglyceride estolides from lesquerella and castor oils." Industrial Crops and Products, 23, 256-263.
Rubio06: Rubio S, Larson TR, Gonzalez-Guzman M, Alejandro S, Graham IA, Serrano R, Rodriguez PL (2006). "An Arabidopsis mutant impaired in coenzyme A biosynthesis is sugar dependent for seedling establishment." Plant Physiol 140(3);830-43. PMID: 16415216
Salaun81: Salaun JP, Benveniste I, Reichhart D, Durst F (1981). "Induction and specificity of a (cytochrome P-450)-dependent laurate in-chain-hydroxylase from higher plant microsomes." Eur J Biochem 119(3);651-5. PMID: 7308207
©2014 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493