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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Enzyme: Dipeptidase 2 / LTD4 dipeptidase 2

Gene: DPEP2 Accession Number: HS09532 (MetaCyc)

Synonyms: UNQ284/PRO323

Species: Homo sapiens

Subunit composition of Dipeptidase 2 / LTD4 dipeptidase 2 = [DPEP2]2
         Dipeptidase 2 = DPEP2

Map Position: [68,399,040 <- 68,412,217]

Unification Links: ArrayExpress:Q9H4A9 , Ensembl:ENSG00000167261 , Entrez-gene:64174 , Entrez-Nucleotide:AJ295149 , Entrez-Nucleotide:AK092884 , Entrez-Nucleotide:BC024021 , Entrez:AAH24021 , Entrez:CAC14667 , GeneCards:LOC64174 , PhylomeDB:Q9H4A9 , Pride:Q9H4A9 , Protein Model Portal:Q9H4A9 , RefSeq:NM_022355 , RefSeq:NP_071750 , SMR:Q9H4A9 , String:9606.ENSP00000268795 , UCSC Human Genome:NM_022355 , UniGene:115537 , UniProt:Q9H4A9

Relationship Links: InterPro:IN-FAMILY:IPR000180 , InterPro:IN-FAMILY:IPR008257 , Panther:IN-FAMILY:PTHR10443 , Pfam:IN-FAMILY:PF01244 , Prosite:IN-FAMILY:PS00869 , Prosite:IN-FAMILY:PS51365

Gene-Reaction Schematic: ?

Instance reaction of [a dipeptide + H2O → 2 amino acids] (3.4.13.19):
i1: L-glutamyl-L-glutamate + H2O → 2 L-glutamate (3.4.13.7)

GO Terms:

Biological Process: GO:0006508 - proteolysis
Molecular Function: GO:0008239 - dipeptidyl-peptidase activity

Credits:
Created 26-Jun-2010 by Trupp M , SRI International


Enzymatic reaction of: Dipeptidase 2

EC Number: 3.4.13.19

a dipeptide + H2O <=> 2 amino acids

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

The reaction is physiologically favored in the direction shown.


Enzymatic reaction of: LTD4 dipeptidase 2

EC Number: 3.4.13.19

leukotriene-D4 + H2O <=> glycine + leukotriene-E4

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

The reaction is physiologically favored in the direction shown.

In Pathways: leukotriene biosynthesis

Exons/Introns:


References

Habib03: Habib GM, Shi ZZ, Cuevas AA, Lieberman MW (2003). "Identification of two additional members of the membrane-bound dipeptidase family." FASEB J 17(10);1313-5. PMID: 12738806


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 20, 2014, biocyc12.