Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
twitter

MetaCyc Enzyme: dihydroxyacetone kinase

Gene: dhaK Accession Number: G-3542 (MetaCyc)

Species: Citrobacter freundii

Subunit composition of dihydroxyacetone kinase = [DhaK]2
         dihydroxyacetone kinase subunit = DhaK

Molecular Weight of Polypeptide: 57 kD (experimental) [Daniel95 ]

Molecular Weight of Multimer: 105 kD (experimental) [Daniel95]

Unification Links: ModBase:P45510 , Protein Model Portal:P45510 , SMR:P45510 , Swiss-Model:P45510 , UniProt:P45510

Relationship Links: Entrez-Nucleotide:RELATED-TO:U09771 , InterPro:IN-FAMILY:IPR004006 , InterPro:IN-FAMILY:IPR004007 , InterPro:IN-FAMILY:IPR012734 , PDB:Structure:1UN8 , PDB:Structure:1UN9 , Pfam:IN-FAMILY:PF02733 , Pfam:IN-FAMILY:PF02734 , Prosite:IN-FAMILY:PS51480 , Prosite:IN-FAMILY:PS51481

Gene-Reaction Schematic: ?

MultiFun Terms: metabolism central intermediary metabolism misc. glycerol metabolism


Enzymatic reaction of: dihydroxyacetone kinase

EC Number: 2.7.1.29

dihydroxyacetone + ATP <=> dihydroxyacetone phosphate + ADP + H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction of enzyme catalysis.

The reaction is irreversible in the direction shown.

In Pathways: superpathway of glycerol degradation to 1,3-propanediol , glycerol degradation II

Activators (Allosteric): Mg2+ [Daniel95] , Ca2+ [Daniel95]

Kinetic Parameters:

Substrate
Km (μM)
Citations
dihydroxyacetone
30.0
[Daniel95]
ATP
70.0
[Daniel95]


References

Daniel95: Daniel R, Stuertz K, Gottschalk G (1995). "Biochemical and molecular characterization of the oxidative branch of glycerol utilization by Citrobacter freundii." J Bacteriol 177(15);4392-401. PMID: 7635824


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, BIOCYC14A.