MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Pseudomonas fluorescens: 2-keto-6-phosphogluconate reductaseInferred from experiment

In Pathway: glucose degradation (oxidative)

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: phosphogluconate 2-dehydrogenase

Enzyme Commission Synonyms: 6-phosphogluconic dehydrogenase, phosphogluconate dehydrogenase, gluconate 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase (NAD), 2-keto-6-phosphogluconate reductase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -6.729309Inferred by computational analysis [Latendresse13]

Citations: [Frampton61]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R02034

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:, Rhea:RELATED-TO:16820, Rhea:RELATED-TO:16824


Frampton61: Frampton EW, Wood WA (1961). "Carbohydrate oxidation by Pseudomonas fluorescens VI. Conversion of 2-keto-6-phosphogluconate to pyruvate." J Biol Chem 236;2571-7. PMID: 13894458

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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