|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
Enzymes and Genes:
|Homo sapiens:||glutathione peroxidase 4: GPX4|
In Pathway: glutathione-peroxide redox reactions
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: phospholipid-hydroperoxide glutathione peroxidase
Enzyme Commission Synonyms: peroxidation-inhibiting protein, PHGPX, peroxidation-inhibiting protein: peroxidase, glutathione (phospholipid hydroperoxide-reducing), phospholipid hydroperoxide glutathione peroxidase, hydroperoxide glutathione peroxidase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -26.941177 [Latendresse13]
Enzyme Commission Summary:
A protein containing a selenocysteine residue. The products of action of EC 22.214.171.124 lipoxygenase on phospholipids can act as acceptors; H2O2 can also act, but much more slowly (cf. EC 126.96.36.199 glutathione peroxidase).
Unification Links: KEGG:R03167
©2015 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493