Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 1.2.99.7

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.2.99.7

Enzymes and Genes:
aldehyde dehydrogenase Inferred from experiment : yagT , yagS , yagR ( Escherichia coli K-12 substr. MG1655 )

Reaction Locations: periplasmic space (sensu Gram-negative Bacteria)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: aldehyde dehydrogenase (FAD-independent)

Enzyme Commission Synonyms: aldehyde oxidase, aldehyde oxidoreductase, Mop, AORDd

Standard Gibbs Free Energy (ΔrG in kcal/mol): -27.93158 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Belongs to the xanthine oxidase family of enzymes.

Citations: [Andrade00, Duarte00, Uchida03, Romao95]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R00544

Relationship Links: BRENDA:EC:1.2.99.7 , ENZYME:EC:1.2.99.7 , IUBMB-ExplorEnz:EC:1.2.99.7 , Rhea:RELATED-TO:13881


References

Andrade00: Andrade SL, Brondino CD, Feio MJ, Moura I, Moura JJ (2000). "Aldehyde oxidoreductase activity in Desulfovibrio alaskensis NCIMB 13491 EPR assignment of the proximal [2Fe-2S] cluster to the Mo site." Eur J Biochem 267(7);2054-61. PMID: 10727945

Duarte00: Duarte RO, Archer M, Dias JM, Bursakov S, Huber R, Moura I, Romao MJ, Moura JJ (2000). "Biochemical/spectroscopic characterization and preliminary X-ray analysis of a new aldehyde oxidoreductase isolated from Desulfovibrio desulfuricans ATCC 27774." Biochem Biophys Res Commun 268(3);745-9. PMID: 10679276

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Romao95: Romao MJ, Archer M, Moura I, Moura JJ, LeGall J, Engh R, Schneider M, Hof P, Huber R (1995). "Crystal structure of the xanthine oxidase-related aldehyde oxido-reductase from D. gigas." Science 270(5239);1170-6. PMID: 7502041

Uchida03: Uchida H, Kondo D, Yamashita A, Nagaosa Y, Sakurai T, Fujii Y, Fujishiro K, Aisaka K, Uwajima T (2003). "Purification and characterization of an aldehyde oxidase from Pseudomonas sp. KY 4690." FEMS Microbiol Lett 229(1);31-6. PMID: 14659539


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Mon Nov 24, 2014, biocyc13.