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MetaCyc Reaction: 2.3.1.22

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.3.1.22

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 2-acylglycerol O-acyltransferase

Enzyme Commission Synonyms: acylglycerol palmitoyltransferase, monoglyceride acyltransferase, acyl coenzyme A-monoglyceride acyltransferase, monoacylglycerol acyltransferase

Taxonomic Range: Fungi , Metazoa

Standard Gibbs Free Energy (ΔrG in kcal/mol): 325.0658 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Various 2-acylglycerols can act as acceptor; palmitoyl-CoA and other long-chain acyl-CoAs can act as donors. The sn-1 position and the sn-3 position are both acylated, at about the same rate.

Citations: [Manganaro85]

Unification Links: KEGG:R01368 , Rhea:16741

Relationship Links: BRENDA:EC:2.3.1.22 , ENZYME:EC:2.3.1.22 , IUBMB-ExplorEnz:EC:2.3.1.22


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Manganaro85: Manganaro F, Kuksis A (1985). "Purification and preliminary characterization of 2-monoacylglycerol acyltransferase from rat intestinal villus cells." Can J Biochem Cell Biol 63(5);341-7. PMID: 4016575


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Fri May 29, 2015, biocyc11.