|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 3.7.1.-
Enzymes and Genes:
2-hydroxy-6-oxohepta-2,4-dienoate hydrolase ( Acidovorax sp. JS42 )
2-hydroxy-6-oxohepta-2,4-dienoate hydrolase : todF ( Pseudomonas putida F1 )
2-hydroxymuconate semialdehyde hydrolase ( Ralstonia pickettii )
2-hydroxy-6-oxohepta-2,4-dienoate hydrolase ( Burkholderia cepacia )
In Pathway: toluene degradation to 2-oxopent-4-enoate I (via o-cresol) , toluene degradation to 2-oxopent-4-enoate (via 4-methylcatechol) , 2-nitrotoluene degradation , toluene degradation to 2-oxopent-4-enoate (via toluene-cis-diol)
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 3.7.1 -- In ketonic substances
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -19.01712 [Latendresse13]
Unification Links: KEGG:R05138
Menn91: Menn FM, Zylstra GJ, Gibson DT (1991). "Location and sequence of the todF gene encoding 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase in Pseudomonas putida F1." Gene 1991;104(1);91-4. PMID: 1916282
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