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MetaCyc Reaction: 2.1.1.129

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 2.1.1.129

Enzymes and Genes:

Mesembryanthemum crystallinum: myo-inositol 4-O-methyltransferaseInferred from experiment: imt1

In Pathway: pinitol biosynthesis I

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: inositol 4-methyltransferase

Enzyme Commission Synonyms: myo-inositol 4-O-methyltransferase, S-adenosyl-L-methionine:myo-inositol 4-O-methyltransferase, myo-inositol 6-O-methyltransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -4.3599854Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
The enzyme from the rice bean Vigna umbellata (Fabaceae) is highly specific for S-adenosyl-L-methionine. The enzyme also methylates 1L-1,2,4/3,5-cyclohexanepentol, 2,4,6/3,5-pentahydroxycyclohexanone, D,L-2,3,4,6/5-pentacyclohexanone and 2,2′-anhydro-2-C-hydroxymethyl-myo-inositol, but at lower rates than that of myo-inositol.

Citations: [Vernon92]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R01190, Rhea:23248

Relationship Links: BRENDA:EC:2.1.1.129, ENZYME:EC:2.1.1.129, IUBMB-ExplorEnz:EC:2.1.1.129


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Vernon92: Vernon DM, Bohnert HJ (1992). "A novel methyl transferase induced by osmotic stress in the facultative halophyte Mesembryanthemum crystallinum." EMBO J 11(6);2077-85. PMID: 1600940


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Sat Apr 30, 2016, biocyc11.