MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Coptis japonica: columbamine O-methyltransferaseInferred from experiment: CoOMT
Papaver somniferum: S-tetrahydrocolumbamine O-methyltransferaseInferred from experiment: MT1

In Pathway: palmatine biosynthesis

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: tetrahydrocolumbamine 2-O-methyltransferase

Enzyme Commission Synonyms: tetrahydrocolumbamine methyltransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -19.899002Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Involved in the biosynthesis of the berberine alkaloids.

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R04077, Rhea:22536

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Tue Dec 1, 2015, biocyc13.