|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
Enzymes and Genes:
|Coptis japonica :||columbamine O-methyltransferase
|Papaver somniferum :||S-tetrahydrocolumbamine O-methyltransferase
In Pathway: palmatine biosynthesis
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: tetrahydrocolumbamine 2-O-methyltransferase
Enzyme Commission Synonyms: tetrahydrocolumbamine methyltransferase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -19.899002 [Latendresse13]
Enzyme Commission Summary:
Involved in the biosynthesis of the berberine alkaloids.
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