MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:

Coptis japonica : columbamine O-methyltransferase Inferred from experiment : CoOMT
Papaver somniferum : S-tetrahydrocolumbamine O-methyltransferase Inferred from experiment : MT1

In Pathway: palmatine biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: tetrahydrocolumbamine 2-O-methyltransferase

Enzyme Commission Synonyms: tetrahydrocolumbamine methyltransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -19.899002 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Involved in the biosynthesis of the berberine alkaloids.

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R04077 , Rhea:22536

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC:


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sun Oct 4, 2015, BIOCYC14B.