Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 2.4.1.117

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.4.1.117

Enzymes and Genes:
UDP-glucose:dolichyl-phosphate glucosyltransferase Inferred from experiment : ALG5 ( Saccharomyces cerevisiae )

In Pathway: dolichyl-diphosphooligosaccharide biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: dolichyl-phosphate β-glucosyltransferase

Enzyme Commission Synonyms: polyprenyl phosphate:UDP-D-glucose glucosyltransferase, UDP-glucose dolichyl-phosphate glucosyltransferase, uridine diphosphoglucose-dolichol glucosyltransferase, UDP-glucose:dolichol phosphate glucosyltransferase, UDP-glucose:dolicholphosphoryl glucosyltransferase, UDP-glucose:dolichyl monophosphate glucosyltransferase, UDP-glucose:dolichyl phosphate glucosyltransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -0.62390137 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Solanesyl phosphate and ficaprenyl phosphate can act as acceptors, but more slowly.

Citations: [Behrens70, Herscovics77, Villemez79]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R01005 , Rhea:15401

Relationship Links: BRENDA:EC:2.4.1.117 , ENZYME:EC:2.4.1.117 , IUBMB-ExplorEnz:EC:2.4.1.117 , UniProt:RELATED-TO:P40350 , UniProt:RELATED-TO:Q9UUT0 , UniProt:RELATED-TO:Q9Y673


References

Behrens70: Behrens NH, Leloir LF (1970). "Dolichol monophosphate glucose: an intermediate in glucose transfer in liver." Proc Natl Acad Sci U S A 66(1);153-9. PMID: 5273893

Herscovics77: Herscovics A, Bugge B, Jeanloz RW (1977). "Glucosyltransferase activity in calf pancreas microsomes. Formation of dolichyl D[14C]glucosyl phosphate and 14C-labeled lipid-linked oligosaccharides from UDP-D-[14C]glucose." J Biol Chem 252(7);2271-7. PMID: 849929

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Villemez79: Villemez CL, Carlo PL (1979). "Properties of a soluble polyprenyl phosphate: UDP-D-glucose glucosyltransferase." J Biol Chem 254(11);4814-9. PMID: 438216


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Nov 23, 2014, BIOCYC13B.