Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 2.4.1.142

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.4.1.142

Enzymes and Genes:
chitobiosyldiphosphodolichol β-mannosyltransferase Inferred from experiment : ALG1 ( Saccharomyces cerevisiae )

In Pathway: dolichyl-diphosphooligosaccharide biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: chitobiosyldiphosphodolichol β-mannosyltransferase

Enzyme Commission Synonyms: guanosine diphosphomannose-dolichol diphosphochitobiose mannosyltransferase, GDP-mannose-dolichol diphosphochitobiose mannosyltransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 6.897827 Inferred by computational analysis [Latendresse13]

Citations: [Takahashi00, Sharma82]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R04502

Relationship Links: BRENDA:EC:2.4.1.142 , ENZYME:EC:2.4.1.142 , IUBMB-ExplorEnz:EC:2.4.1.142


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Sharma82: Sharma CB, Lehle L, Tanner W (1982). "Solubilization and characterization of the initial enzymes of the dolichol pathway from yeast." Eur J Biochem 126(2);319-25. PMID: 6215245

Takahashi00: Takahashi T, Honda R, Nishikawa Y (2000). "Cloning of the human cDNA which can complement the defect of the yeast mannosyltransferase I-deficient mutant alg 1." Glycobiology 10(3);321-7. PMID: 10704531


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, BIOCYC14B.