|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminyltransferase
Enzyme Commission Synonyms: uridine diphosphoacetylglucosamine-dolichol phosphate acetylglucosaminyltransferase, dolichyl phosphate acetylglucosaminyltransferase, dolichyl phosphate N-acetylglucosaminyltransferase, UDP-N-acetylglucosamine-dolichol phosphate N-acetylglucosaminyltransferase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -0.6240845 [Latendresse13]
Enzyme Commission Summary:
The enzyme, characterized from the methanogenic archaeon Methanococcus voltae, initiates N-linked glycosylation in that organism. The enzyme differs from the eukaryotic enzyme, which leaves one additional phosphate group on the dolichyl product (cf. EC 22.214.171.124, UDP-N-acetylglucosamine—dolichyl-phosphate N-acetylglucosaminephosphotransferase).
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