MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Instance reaction:
ω-saturated C55 dolichol phosphate + UDP-N-acetyl-α-D-glucosamine → N-acetyl-α-D-glucosaminyl-(C55 ω-saturated dolichyl phosphate) + UDP (

Enzyme Commission Primary Name: dolichyl-phosphate α-N-acetylglucosaminyltransferase

Enzyme Commission Synonyms: uridine diphosphoacetylglucosamine-dolichol phosphate acetylglucosaminyltransferase, dolichyl phosphate acetylglucosaminyltransferase, dolichyl phosphate N-acetylglucosaminyltransferase, UDP-N-acetylglucosamine-dolichol phosphate N-acetylglucosaminyltransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -0.6240845 Inferred by computational analysis [Latendresse13]

Citations: [Leloir73, Molnar71, Tetas70, Warren74]

Unification Links: KEGG:R01008 , Rhea:14693

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC:


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Leloir73: Leloir LF, Staneloni RJ, Carminatti H, Behrens NH (1973). "The biosynthesis of a N,N'-diacetylchitobiose containing lipid by liver microsomes. A probable dolichol pyrophosphate derivative." Biochem Biophys Res Commun 52(4);1285-92. PMID: 4717748

Molnar71: Molnar J, Chao H, Ikehara Y (1971). "Phosphoryl-N-acetylglucosamine transfer to a lipid acceptor of liver microsomal preparations." Biochim Biophys Acta 239(3);401-10. PMID: 5113503

Tetas70: Tetas M, Chao H, Molnar J (1970). "Incorporation of carbohydrates into endogenous acceptors of liver microsomal fractions." Arch Biochem Biophys 138(1);135-46. PMID: 4315690

Warren74: Warren CD, Jeanloz RW (1974). "Chemical synthesis of P1-2-acetamido-2-deoxy-alpha-D-glucopyranosyl P2-dolichyl pyrophosphate." Carbohydr Res 37(1);252-60. PMID: 4371972

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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