MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide β-1,6-N-acetylglucosaminyltransferase

Enzyme Commission Synonyms: uridine diphosphoacetylglucosamine-acetyllactosaminide β1->6-acetylglucosaminyltransferase, UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-N-acetyl-β-D-glucosaminyl-1,3-β-D-galactosyl-1,4-β-D-glucosylceramide β-1,6-N-acetylglucosaminyltransferase, UDP-N-acetyl-D-glucosamine:D-galactosyl-(1->4)-N-acetyl-β-D-glucosaminyl-(1->3)-β-D-galactosyl-(1->4)-β-D-glucosyl(1↔1)ceramide 6-β-N-acetylglucosaminyltransferase

Standard Gibbs Free Energy (ΔrG): -126.627075 kcal/molInferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Requires Mn2+.

Citations: [Basu84]

Unification Links: KEGG:R04654, Rhea:18025

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Basu84: Basu M, Basu S (1984). "Biosynthesis in vitro of Ii core glycosphingolipids from neolactotetraosylceramide by beta 1-3- and beta 1-6-N-acetylglucosaminyltransferases from mouse T-lymphoma." J Biol Chem 259(20);12557-62. PMID: 6238026

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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