Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 2.6.1.33

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.6.1.33

Enzymes and Genes:
dTDP-4-amino-4,6-dideoxy-D-glucose transaminase Inferred from experiment : vioA ( Escherichia coli O7:K1 )
dTDP-4-amino-4,6-dideoxy-D-glucose transaminase Inferred from experiment : eryCIV ( Saccharopolyspora erythraea NRRL 2338 )
dTDP-4-amino-4,6-dideoxy-D-glucose transaminase Inferred from experiment : desI ( Streptomyces venezuelae )

In Pathway: dTDP-N-acetylviosamine biosynthesis , dTDP-D-desosamine biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: dTDP-4-amino-4,6-dideoxy-D-glucose transaminase

Enzyme Commission Synonyms: thymidine diphospho-4-amino-4,6-dideoxyglucose aminotransferase, thymidine diphospho-4-amino-6-deoxyglucose aminotransferase, thymidine diphospho-4-keto-6-deoxy-D-glucose transaminase, thymidine diphospho-4-keto-6-deoxy-D-glucose-glutamic transaminase, TDP-4-keto-6-deoxy-D-glucose transaminase, VioA, dTDP-4-amino-4,6-dideoxy-D-glucose:2-oxoglutarate aminotransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -3.2200317 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
A pyridoxal-phosphate protein.

Citations: [Wang07f, Matsuhashi66]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R02773 , Rhea:19085

Relationship Links: BRENDA:EC:2.6.1.33 , ENZYME:EC:2.6.1.33 , IUBMB-ExplorEnz:EC:2.6.1.33


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Matsuhashi66: Matsuhashi M, Strominger JL (1966). "Thymidine diphosphate 4-acetamido-2,6-dideoxyhexoses. 3. Purification and properties of thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase from Escherichia coli strain B." J Biol Chem 241(20);4738-44. PMID: 5332731

Wang07f: Wang Y, Xu Y, Perepelov AV, Qi Y, Knirel YA, Wang L, Feng L (2007). "Biochemical characterization of dTDP-D-Qui4N and dTDP-D-Qui4NAc biosynthetic pathways in Shigella dysenteriae type 7 and Escherichia coli O7." J Bacteriol 189(23);8626-35. PMID: 17905981


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Mon Nov 24, 2014, BIOCYC13B.