Metabolic Modeling Tutorial
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BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Reaction: 2.6.1.33

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.6.1.33

Enzymes and Genes:
dTDP-4-amino-4,6-dideoxy-D-glucose transaminase Inferred from experiment : vioA ( Escherichia coli O7:K1 )
dTDP-4-amino-4,6-dideoxy-D-glucose transaminase Inferred from experiment : eryCIV ( Saccharopolyspora erythraea NRRL 2338 )
dTDP-4-amino-4,6-dideoxy-D-glucose transaminase Inferred from experiment : desI ( Streptomyces venezuelae )

In Pathway: dTDP-N-acetylviosamine biosynthesis , dTDP-D-desosamine biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: dTDP-4-amino-4,6-dideoxy-D-glucose transaminase

Enzyme Commission Synonyms: thymidine diphospho-4-amino-4,6-dideoxyglucose aminotransferase, thymidine diphospho-4-amino-6-deoxyglucose aminotransferase, thymidine diphospho-4-keto-6-deoxy-D-glucose transaminase, thymidine diphospho-4-keto-6-deoxy-D-glucose-glutamic transaminase, TDP-4-keto-6-deoxy-D-glucose transaminase, VioA, dTDP-4-amino-4,6-dideoxy-D-glucose:2-oxoglutarate aminotransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -3.2200317 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
A pyridoxal-phosphate protein.

Citations: [Wang07d, Matsuhashi66]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R02773 , Rhea:19085

Relationship Links: BRENDA:EC:2.6.1.33 , ENZYME:EC:2.6.1.33 , IUBMB-ExplorEnz:EC:2.6.1.33


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Matsuhashi66: Matsuhashi M, Strominger JL (1966). "Thymidine diphosphate 4-acetamido-2,6-dideoxyhexoses. 3. Purification and properties of thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase from Escherichia coli strain B." J Biol Chem 241(20);4738-44. PMID: 5332731

Wang07d: Wang Y, Xu Y, Perepelov AV, Qi Y, Knirel YA, Wang L, Feng L (2007). "Biochemical characterization of dTDP-D-Qui4N and dTDP-D-Qui4NAc biosynthetic pathways in Shigella dysenteriae type 7 and Escherichia coli O7." J Bacteriol 189(23);8626-35. PMID: 17905981


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Dec 21, 2014, BIOCYC13B.