MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:

Saccharomyces cerevisiae : UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglocosaminephosphotransferase Inferred from experiment : ALG7

In Pathway: protein N-glycosylation (eukaryotic, high mannose)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: UDP-N-acetylglucosamine—dolichyl-phosphate N-acetylglucosaminephosphotransferase

Enzyme Commission Synonyms: UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase, UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase, UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase, uridine diphosphoacetylglucosamine-dolichyl phosphate acetylglucosamine-1-phosphotransferase, chitobiosylpyrophosphoryldolichol synthase, dolichol phosphate N-acetylglucosamine-1-phosphotransferase, UDP-acetylglucosamine-dolichol phosphate acetylglucosamine phosphotransferase, UDP-acetylglucosamine-dolichol phosphate acetylglucosamine-1-phosphotransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 1.8310547e-4 Inferred by computational analysis [Latendresse13]

Citations: [Villemez80, Sharma82]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R01007 , Rhea:13289

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC: , UniProt:RELATED-TO:O22211 , UniProt:RELATED-TO:P07286 , UniProt:RELATED-TO:P23338 , UniProt:RELATED-TO:P39465 , UniProt:RELATED-TO:P42864 , UniProt:RELATED-TO:P42867 , UniProt:RELATED-TO:P42881 , UniProt:RELATED-TO:P96000 , UniProt:RELATED-TO:Q9M2M5 , UniProt:RELATED-TO:Q9UY90 , UniProt:RELATED-TO:Q58513


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Sharma82: Sharma CB, Lehle L, Tanner W (1982). "Solubilization and characterization of the initial enzymes of the dolichol pathway from yeast." Eur J Biochem 126(2);319-25. PMID: 6215245

Villemez80: Villemez CL, Carlo PL (1980). "Properties of a soluble polyprenyl phosphate. UDP-D-N-acetylglucosamine N-acetylglucosamine-1-phosphate transferase." J Biol Chem 255(17);8174-8. PMID: 6447695

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sat Oct 10, 2015, biocyc12.