|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
Enzymes and Genes:
|Arabidopsis thaliana col :||acylhydrolase
|Saccharomyces cerevisiae :||monoacylglycerol lipase
In Pathway: triacylglycerol degradation
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
1-oleoyl-sn-glycerol + H2O → glycerol + oleate + H+ (22.214.171.124)
Enzyme Commission Primary Name: acylglycerol lipase
Enzyme Commission Synonyms: monoacylglycerol lipase, monoacylglycerolipase, monoglyceride lipase, monoglyceride hydrolase, fatty acyl monoester lipase, monoacylglycerol hydrolase, monoglyceridyllipase, monoglyceridase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 66.41072 [Latendresse13]
Instance reaction of [a 1-monoglyceride + H2O → a fatty acid + glycerol + H+] (126.96.36.199):
i8: 1-oleoyl-sn-glycerol + H2O → glycerol + oleate + H+ (188.8.131.52)
Instance reactions of [a phosphatidylcholine + H2O → a 1-acyl 2-lyso-phosphatidylcholine + a long-chain fatty acid + H+] (184.108.40.206):
i5: 1,2-dipalmitoyl-phosphatidylcholine + H2O → 1-16:0-2-lysophosphatidylcholine + palmitate + H+ (220.127.116.11)
i6: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + H2O → 1-18:2-lysophosphatidylcholine + palmitate + H+ (18.104.22.168)
Mentlein80: Mentlein R, Heiland S, Heymann E (1980). "Simultaneous purification and comparative characterization of six serine hydrolases from rat liver microsomes." Arch Biochem Biophys 200(2);547-59. PMID: 6776896
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