Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 3.1.1.75

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.1.1.75

Enzymes and Genes:
poly(3-hydroxybutyrate) depolymerase Inferred from experiment : phaZ7 ( Paucimonas lemoignei )

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Marked as unbalanced.

Enzyme Commission Primary Name: poly(3-hydroxybutyrate) depolymerase

Enzyme Commission Synonyms: PHB depolymerase, poly(3HB) depolymerase, poly[(R)-hydroxyalkanoic acid] depolymerase, poly(HA) depolymerase, poly(HASCL) depolymerase, poly[(R)-3-hydroxybutyrate] hydrolase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -13.819489 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Reaction also occurs with esters of other short-chain-length (C(1)-C(5)) hydroxyalkanoic acids (HA). There are two types of polymers: native (intracellular) granules are amorphous and have an intact surface layer; denatured (extracellular) granules either have no surface layer or a damaged surface layer and are partially crystalline.

Citations: [Garcia99, Jendrossek01]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:3.1.1.75 , ENZYME:EC:3.1.1.75 , IUBMB-ExplorEnz:EC:3.1.1.75


References

Garcia99: Garcia B, Olivera ER, Minambres B, Fernandez-Valverde M, Canedo LM, Prieto MA, Garcia JL, Martinez M, Luengo JM (1999). "Novel biodegradable aromatic plastics from a bacterial source. Genetic and biochemical studies on a route of the phenylacetyl-coa catabolon." J Biol Chem 274(41);29228-41. PMID: 10506180

Jendrossek01: Jendrossek D (2001). "Microbial degradation of polyesters." Adv Biochem Eng Biotechnol 71;293-325. PMID: 11217416

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Nov 21, 2014, BIOCYC13B.