MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Instance reaction:
L-methionyl-L-alanine dipeptide + H2O → L-methionine + L-alanine (

Enzyme Commission Primary Name: Met-Xaa dipeptidase

Enzyme Commission Synonyms: methionyl dipeptidase, dipeptidase M, Met-X dipeptidase

Standard Gibbs Free Energy (ΔrG): 91.97708 kcal/molInferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
This enzyme catlayzes hydrolysis of Met-|-Xaa dipeptides.

A Mn2+-activated Escherichia coli enzyme with thiol dependence.

Citations: [Brown73b]

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Brown73b: Brown JL (1973). "Purification and properties of dipeptidase M from Escherichia coli B." J Biol Chem 248(2);409-16. PMID: 4567782

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 20.0 (software by SRI International) on Thu May 5, 2016, BIOCYC12.