Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 3.4.13.5

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.4.13.5

Supersedes EC number: 3.4.3.4

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: Xaa-methyl-His dipeptidase

Enzyme Commission Synonyms: anserinase, aminoacyl-methylhistidine dipeptidase, acetylhistidine deacetylase, N-acetylhistidine deacetylase, α-N-acetyl-L-histidine aminohydrolase, X-methyl-His dipeptidase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -21.005234 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Hydrolysis of anserine, carnosine, homocarnosine, glycyl-L-leucine and other dipeptides with broad specificity.

Is identical with acetylhistidine deacetylase.

Citations: [JONES55, Baslow67, Lenney78]

Relationship Links: BRENDA:EC:3.4.13.5 , ENZYME:EC:3.4.13.5 , IUBMB-ExplorEnz:EC:3.4.13.5


References

Baslow67: Baslow MH, Lenney JF (1967). "Alpha-N-acetyl-L-histidine amidohydrolase activity from the brain of the skipjack tuna Katsuwonus pelamis." Can J Biochem 45(2);337-40. PMID: 6067033

JONES55: JONES NR (1955). "The free amino acids of fish; 1-methylhistidine and beta-alanine liberation by skeletal muscle anserinase of codling (Gadus callarias)." Biochem J 60(1);81-7. PMID: 14363188

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Lenney78: Lenney JF, Baslow MH, Sugiyama GH (1978). "Similarity of tuna N-acetylhistidine deacetylase and cod fish anserinase." Comp Biochem Physiol B 61(2);253-8. PMID: 318374


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Wed Nov 26, 2014, biocyc13.