twitter

MetaCyc Reaction: 3.4.13.5

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.4.13.5

Supersedes EC number: 3.4.3.4

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: Xaa-methyl-His dipeptidase

Enzyme Commission Synonyms: anserinase, aminoacyl-methylhistidine dipeptidase, acetylhistidine deacetylase, N-acetylhistidine deacetylase, α-N-acetyl-L-histidine aminohydrolase, X-methyl-His dipeptidase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -21.005234 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Hydrolysis of anserine, carnosine, homocarnosine, glycyl-L-leucine and other dipeptides with broad specificity.

Is identical with acetylhistidine deacetylase.

Citations: [JONES55, Baslow67, Lenney78]

Relationship Links: BRENDA:EC:3.4.13.5 , ENZYME:EC:3.4.13.5 , IUBMB-ExplorEnz:EC:3.4.13.5


References

Baslow67: Baslow MH, Lenney JF (1967). "Alpha-N-acetyl-L-histidine amidohydrolase activity from the brain of the skipjack tuna Katsuwonus pelamis." Can J Biochem 45(2);337-40. PMID: 6067033

JONES55: JONES NR (1955). "The free amino acids of fish; 1-methylhistidine and beta-alanine liberation by skeletal muscle anserinase of codling (Gadus callarias)." Biochem J 60(1);81-7. PMID: 14363188

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Lenney78: Lenney JF, Baslow MH, Sugiyama GH (1978). "Similarity of tuna N-acetylhistidine deacetylase and cod fish anserinase." Comp Biochem Physiol B 61(2);253-8. PMID: 318374


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Wed Jul 29, 2015, BIOCYC13A.