MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Mass balance status: The left side is missing: R: 1 N: 1 C: 2 O: 1 H: 2

Enzyme Commission Primary Name: carboxypeptidase A2

Enzyme Commission Synonyms: CPA2

Taxonomic Range: Metazoa

Standard Gibbs Free Energy (ΔrG in kcal/mol): -48.12524Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
This enzyme is similar to that of carboxypeptidase A (EC, but with a preference for bulkier C-terminal residues.

Isolated from rat pancreas but not present in cattle pancreas. In peptidase family M14 (carboxypeptidase A family).

Citations: [Dehm70]

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:, UniProt:RELATED-TO:P19222, UniProt:RELATED-TO:P48052


Dehm70: Dehm P, Nordwig A (1970). "The cleavage of prolyl peptides by kidney peptidases. Isolation of a microsomal carboxypeptidase from swine kidney." Eur J Biochem 17(2);372-7. PMID: 5500406

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Wed May 4, 2016, biocyc14.