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MetaCyc Reaction: 3.5.1.69

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.5.1.69

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balance undetermined; a substrate lacks a chemical formula

Enzyme Commission Primary Name: glycosphingolipid deacylase

Enzyme Commission Synonyms: glycosphingolipid ceramide deacylase

Enzyme Commission Summary:
This enzyme catalyzes hydrolysis of gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives.

Does not act on sphingolipids such as ceramide. Not identical with EC 3.5.1.23 ceramidase.

Citations: [Hirabayashi88]

Relationship Links: BRENDA:EC:3.5.1.69 , ENZYME:EC:3.5.1.69 , IUBMB-ExplorEnz:EC:3.5.1.69


References

Hirabayashi88: Hirabayashi Y, Kimura M, Matsumoto M, Yamamoto K, Kadowaki S, Tochikura T (1988). "A novel glycosphingolipid hydrolyzing enzyme, glycosphingolipid ceramide deacylase, which cleaves the linkage between the fatty acid and sphingosine base in glycosphingolipids." J Biochem 103(1);1-4. PMID: 3360750


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Fri Sep 4, 2015, BIOCYC14A.