MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Mass balance status: Balance undetermined; a substrate lacks a chemical formula

Enzyme Commission Primary Name: glycosphingolipid deacylase

Enzyme Commission Synonyms: glycosphingolipid ceramide deacylase

Enzyme Commission Summary:
This enzyme catalyzes hydrolysis of gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives.

Does not act on sphingolipids such as ceramide. Not identical with EC ceramidase.

Citations: [Hirabayashi88]

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Hirabayashi88: Hirabayashi Y, Kimura M, Matsumoto M, Yamamoto K, Kadowaki S, Tochikura T (1988). "A novel glycosphingolipid hydrolyzing enzyme, glycosphingolipid ceramide deacylase, which cleaves the linkage between the fatty acid and sphingosine base in glycosphingolipids." J Biochem 103(1);1-4. PMID: 3360750

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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