|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balance undetermined; a substrate lacks a chemical formula
Enzyme Commission Primary Name: glycosphingolipid deacylase
Enzyme Commission Synonyms: glycosphingolipid ceramide deacylase
Enzyme Commission Summary:
This enzyme catalyzes hydrolysis of gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives.
Does not act on sphingolipids such as ceramide. Not identical with EC 126.96.36.199 ceramidase.
Hirabayashi88: Hirabayashi Y, Kimura M, Matsumoto M, Yamamoto K, Kadowaki S, Tochikura T (1988). "A novel glycosphingolipid hydrolyzing enzyme, glycosphingolipid ceramide deacylase, which cleaves the linkage between the fatty acid and sphingosine base in glycosphingolipids." J Biochem 103(1);1-4. PMID: 3360750
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