|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 188.8.131.52
Enzymes and Genes:
|Pseudomonas nitroreducens :||2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoate hydrolase [multifunctional]
|Rhodococcus jostii RHA1 :||2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 2,6-dioxo-6-phenylhexa-3-enoate hydrolase
Enzyme Commission Synonyms: HOHPDA hydrolase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -10.087128 [Latendresse13]
Enzyme Commission Summary:
Cleaves the products from biphenol, 3-isopropylcatechol and 3-methylcatechol produced by EC 184.108.40.206 biphenyl-2,3-diol 1,2-dioxygenase, by ring-fission at a -CO-C bond. Involved in the breakdown of biphenyl-related compounds by Pseudomonas sp.
Omori86: Omori, T., Sugimura, K., Ishigooka, H., Minoda, Y. (1986). "Purification and some properties of a 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolyzing enzyme from Pseudomonas cruciviae S93 B1 involved in the degradation of biphenyl." Agric. Biol. Chem. 50: 931-937.
©2014 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493