|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 188.8.131.52
Enzymes and Genes:
|Pseudomonas nitroreducens:||2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoate hydrolase [multifunctional]: hbpD|
|Rhodococcus jostii RHA1:||2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase: bphD|
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 2,6-dioxo-6-phenylhexa-3-enoate hydrolase
Enzyme Commission Synonyms: HOHPDA hydrolase
Standard Gibbs Free Energy (ΔrG'°): -10.087128 kcal/mol [Latendresse13]
Enzyme Commission Summary:
Cleaves the products from biphenol, 3-isopropylcatechol and 3-methylcatechol produced by EC 184.108.40.206 biphenyl-2,3-diol 1,2-dioxygenase, by ring-fission at a -CO-C bond. Involved in the breakdown of biphenyl-related compounds by Pseudomonas sp.
Omori86: Omori, T., Sugimura, K., Ishigooka, H., Minoda, Y. (1986). "Purification and some properties of a 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolyzing enzyme from Pseudomonas cruciviae S93 B1 involved in the degradation of biphenyl." Agric. Biol. Chem. 50: 931-937.
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