MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:
4-hydroxybenzoate-CoA ligase / benzoate-CoA ligase Inferred from experiment : hbaA ( Rhodopseudomonas palustris CGA009 )
4-hydroxybenzoate-CoA ligase Inferred from experiment ( Thauera aromatica )

In Pathway: phenol degradation II (anaerobic) , 4-coumarate degradation (anaerobic)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 4-hydroxybenzoate—CoA ligase

Enzyme Commission Synonyms: 4-hydroxybenzoate-CoA synθse, 4-hydroxybenzoate-coenzyme A ligase (AMP-forming), 4-hydroxybenzoyl coenzyme A synθse, 4-hydroxybenzoyl-CoA ligase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -12.71167 Inferred by computational analysis [Latendresse13]

Citations: [Merkel89]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R01300 , Rhea:23116

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC: , UniProt:RELATED-TO:Q53005


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Merkel89: Merkel SM, Eberhard AE, Gibson J, Harwood CS (1989). "Involvement of coenzyme A thioesters in anaerobic metabolism of 4-hydroxybenzoate by Rhodopseudomonas palustris." J Bacteriol 171(1);1-7. PMID: 2914844

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sat Mar 28, 2015, biocyc12.