Metabolic Modeling Tutorial
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BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Reaction: 6.2.1.27

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 6.2.1.27

Enzymes and Genes:
4-hydroxybenzoate-CoA ligase / benzoate-CoA ligase Inferred from experiment : hbaA ( Rhodopseudomonas palustris CGA009 )
4-hydroxybenzoate-CoA ligase Inferred from experiment ( Thauera aromatica )

In Pathway: phenol degradation II (anaerobic) , 4-coumarate degradation (anaerobic)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 4-hydroxybenzoate—CoA ligase

Enzyme Commission Synonyms: 4-hydroxybenzoate-CoA synθse, 4-hydroxybenzoate-coenzyme A ligase (AMP-forming), 4-hydroxybenzoyl coenzyme A synθse, 4-hydroxybenzoyl-CoA ligase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -12.71167 Inferred by computational analysis [Latendresse13]

Citations: [Merkel89]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R01300 , Rhea:23116

Relationship Links: BRENDA:EC:6.2.1.27 , ENZYME:EC:6.2.1.27 , IUBMB-ExplorEnz:EC:6.2.1.27 , UniProt:RELATED-TO:Q53005


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Merkel89: Merkel SM, Eberhard AE, Gibson J, Harwood CS (1989). "Involvement of coenzyme A thioesters in anaerobic metabolism of 4-hydroxybenzoate by Rhodopseudomonas palustris." J Bacteriol 171(1);1-7. PMID: 2914844


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Mon Dec 22, 2014, biocyc11.