|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
In Pathway: bile acid biosynthesis, neutral pathway
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 3α,7α-dihydroxy-5β-cholestanate—CoA ligase
Enzyme Commission Synonyms: 3α,7α-dihydroxy-5β-cholestanoyl coenzyme A synθse, DHCA-CoA ligase, 3α,7α-dihydroxy-5β-cholestanate:CoA ligase (AMP-forming)
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -12.711731 [Latendresse, 2013]
Prydz88: Prydz K, Kase BF, Bjorkhem I, Pedersen JI (1988). "Subcellular localization of 3 alpha, 7 alpha-dihydroxy- and 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoyl-coenzyme A ligase(s) in rat liver." J Lipid Res 29(8);997-1004. PMID: 3183523
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