Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 6.2.1.28

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 6.2.1.28

Enzymes and Genes:
bile acid CoA ligase Inferred from experiment : Slc27a5 ( Rattus norvegicus )

In Pathway: bile acid biosynthesis, neutral pathway

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 3α,7α-dihydroxy-5β-cholestanate—CoA ligase

Enzyme Commission Synonyms: 3α,7α-dihydroxy-5β-cholestanoyl coenzyme A synθse, DHCA-CoA ligase, 3α,7α-dihydroxy-5β-cholestanate:CoA ligase (AMP-forming)

Standard Gibbs Free Energy (ΔrG in kcal/mol): -12.711731 Inferred by computational analysis [Latendresse, 2013]

Citations: [Prydz88]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R04507 , Rhea:21776

Relationship Links: BRENDA:EC:6.2.1.28 , ENZYME:EC:6.2.1.28 , IUBMB-ExplorEnz:EC:6.2.1.28


References

Latendresse, 2013: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Prydz88: Prydz K, Kase BF, Bjorkhem I, Pedersen JI (1988). "Subcellular localization of 3 alpha, 7 alpha-dihydroxy- and 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoyl-coenzyme A ligase(s) in rat liver." J Lipid Res 29(8);997-1004. PMID: 3183523


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Nov 22, 2014, BIOCYC14B.