Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Reaction: 6.2.1.28

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 6.2.1.28

Enzymes and Genes:
bile acid CoA ligase Inferred from experiment : Slc27a5 ( Rattus norvegicus )

In Pathway: bile acid biosynthesis, neutral pathway

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 3α,7α-dihydroxy-5β-cholestanate—CoA ligase

Enzyme Commission Synonyms: 3α,7α-dihydroxy-5β-cholestanoyl coenzyme A synθse, DHCA-CoA ligase, 3α,7α-dihydroxy-5β-cholestanate:CoA ligase (AMP-forming)

Standard Gibbs Free Energy (ΔrG in kcal/mol): -12.711731 Inferred by computational analysis [Latendresse13]

Citations: [Prydz88]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R04507 , Rhea:21776

Relationship Links: BRENDA:EC:6.2.1.28 , ENZYME:EC:6.2.1.28 , IUBMB-ExplorEnz:EC:6.2.1.28


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Prydz88: Prydz K, Kase BF, Bjorkhem I, Pedersen JI (1988). "Subcellular localization of 3 alpha, 7 alpha-dihydroxy- and 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoyl-coenzyme A ligase(s) in rat liver." J Lipid Res 29(8);997-1004. PMID: 3183523


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Dec 21, 2014, biocyc14.