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MetaCyc Reaction: 6.2.1.28

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 6.2.1.28

Enzymes and Genes:

Rattus norvegicus: bile acid CoA ligaseInferred from experiment: Slc27a5

In Pathway: bile acid biosynthesis, neutral pathway

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 3α,7α-dihydroxy-5β-cholestanate—CoA ligase

Enzyme Commission Synonyms: 3α,7α-dihydroxy-5β-cholestanoyl coenzyme A synthetase, DHCA-CoA ligase, 3α,7α-dihydroxy-5β-cholestanate:CoA ligase (AMP-forming)

Standard Gibbs Free Energy (ΔrG in kcal/mol): -12.711731Inferred by computational analysis [Latendresse13]

Citations: [Prydz88]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R04507, Rhea:21776

Relationship Links: BRENDA:EC:6.2.1.28, ENZYME:EC:6.2.1.28, IUBMB-ExplorEnz:EC:6.2.1.28


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Prydz88: Prydz K, Kase BF, Bjorkhem I, Pedersen JI (1988). "Subcellular localization of 3 alpha, 7 alpha-dihydroxy- and 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoyl-coenzyme A ligase(s) in rat liver." J Lipid Res 29(8);997-1004. PMID: 3183523


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Mon May 2, 2016, biocyc11.