|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
Enzymes and Genes:
|Rattus norvegicus:||bile acid CoA ligase: Slc27a5|
In Pathway: bile acid biosynthesis, neutral pathway
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 3α,7α-dihydroxy-5β-cholestanate—CoA ligase
Enzyme Commission Synonyms: 3α,7α-dihydroxy-5β-cholestanoyl coenzyme A synthetase, DHCA-CoA ligase, 3α,7α-dihydroxy-5β-cholestanate:CoA ligase (AMP-forming)
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -12.711731 [Latendresse13]
Prydz88: Prydz K, Kase BF, Bjorkhem I, Pedersen JI (1988). "Subcellular localization of 3 alpha, 7 alpha-dihydroxy- and 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoyl-coenzyme A ligase(s) in rat liver." J Lipid Res 29(8);997-1004. PMID: 3183523
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