MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:

Rattus norvegicus : bile acid CoA ligase Inferred from experiment : Slc27a5

In Pathway: bile acid biosynthesis, neutral pathway

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 3α,7α-dihydroxy-5β-cholestanate—CoA ligase

Enzyme Commission Synonyms: 3α,7α-dihydroxy-5β-cholestanoyl coenzyme A synthetase, DHCA-CoA ligase, 3α,7α-dihydroxy-5β-cholestanate:CoA ligase (AMP-forming)

Standard Gibbs Free Energy (ΔrG in kcal/mol): -12.711731 Inferred by computational analysis [Latendresse13]

Citations: [Prydz88]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R04507 , Rhea:21776

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC:


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Prydz88: Prydz K, Kase BF, Bjorkhem I, Pedersen JI (1988). "Subcellular localization of 3 alpha, 7 alpha-dihydroxy- and 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoyl-coenzyme A ligase(s) in rat liver." J Lipid Res 29(8);997-1004. PMID: 3183523

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Tue Oct 6, 2015, biocyc13.