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MetaCyc Reaction: 2.5.1.4

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.5.1.4

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: adenosylmethionine cyclotransferase

Enzyme Commission Synonyms: adenosylmethioninase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 18.969002 Inferred by computational analysis [Latendresse13]

Citations: [MUDD59, MUDD59a]

Unification Links: KEGG:R00180 , Rhea:21932

Relationship Links: BRENDA:EC:2.5.1.4 , ENZYME:EC:2.5.1.4 , IUBMB-ExplorEnz:EC:2.5.1.4


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

MUDD59: MUDD SH (1959). "The mechanism of the enzymatic cleavage of S-adenosylmethionine to alpha-amino-gamma-butyrolactone." J Biol Chem 234(7);1784-6. PMID: 13672964

MUDD59a: MUDD SH (1959). "Enzymatic cleavage of S-adenosylmethionine." J Biol Chem 234(1);87-92. PMID: 13610898


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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