|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 184.108.40.206
Enzymes and Genes:
|Cupriavidus metallidurans CH34:||kynurenine formamidase: kynB|
|Mus musculus:||arylformamidase: Afmid|
|Saccharomyces cerevisiae:||arylformamidase: BNA3|
|Streptomyces anulatus:||arylformamidase: acmF|
|Streptomyces parvulus:||kynurenine formamidase I|
kynurenine formamidase II
In Pathway: L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde, L-tryptophan degradation I (via anthranilate), L-tryptophan degradation XI (mammalian, via kynurenine), 3-hydroxy-4-methyl-anthranilate biosynthesis
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: arylformamidase
Enzyme Commission Synonyms: kynurenine formamidase, formylase, formylkynureninase, formylkynurenine formamidase, formamidase I, formamidase II
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -1.1171227 [Latendresse13]
Enzyme Commission Summary:
Also acts on other aromatic formylamines.
Hayaishi51: Hayaishi O, Stanier RY (1951). "The bacterial oxidation of tryptophan. III. Enzymatic activities of cell-free extracts from bacteria employing the aromatic pathway." J Bacteriol 62(6);691-709. PMID: 14907621
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