|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 1.1.1.-
Enzymes and Genes:
|Clostridium scindens VPI 12708 :||3α-hydroxysteroid dehydrogenase 1
3α-hydroxysteroid dehydrogenase 2 : baiA2
3α-hydroxysteroid dehydrogenase 3 : baiA3
|Homo sapiens :||3α hydroxysteroid dehydrogenase III
retinol dehydrogenase 9 : DHRS9
In Pathway: cholate degradation (bacteria, anaerobic)
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 1.1.1 -- With NAD(+) or NADP(+) as acceptor
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -10.649414 [Latendresse13]
Instance reactions of [allopregnanolone + NAD(P)+ ↔ 5-α-pregnane-3,20-dione + NAD(P)H + H+] (220.127.116.11):
i1: allopregnanolone + NAD+ → 5-α-pregnane-3,20-dione + NADH + H+ (1.1.-.-)
i2: allopregnanolone + NADP+ ← 5-α-pregnane-3,20-dione + NADPH + H+ (18.104.22.1688)
Instance reactions of [testosterone + NAD(P)+ → androst-4-ene-3,17-dione + NAD(P)H + H+] (22.214.171.124):
i3: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH + H+ (126.96.36.199)
i4: testosterone + NADP+ ← androst-4-ene-3,17-dione + NADPH + H+ (188.8.131.52)
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