MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Escherichia coli K-12 substr. MG1655: β-D-glucuronidaseInferred from experiment: uidA

In Pathway: β-D-glucuronide and D-glucuronate degradation

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: β-glucuronidase

Enzyme Commission Synonyms: β-glucuronide glucuronohydrolase glucuronidase, exo-β-D-glucuronidase, ketodase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 68.784836Inferred by computational analysis [Latendresse13]

Citations: [Doyle55, FISHMAN55, WAKABAYASHI61]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R01478

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:, UniProt:RELATED-TO:P05804, UniProt:RELATED-TO:P06760, UniProt:RELATED-TO:P08236, UniProt:RELATED-TO:P12265


Doyle55: Doyle ML, Katzman PA, Doisy EA (1955). "Production and properties of bacterial beta-glucuronidase." J Biol Chem 217(2);921-30. PMID: 13271452

FISHMAN55: FISHMAN WH (1955). "Not Available." Adv Enzymol Relat Subj Biochem 16;361-409. PMID: 14376216

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

WAKABAYASHI61: WAKABAYASHI M, FISHMAN WH (1961). "The comparative ability of beta-glucuronidase preparations (liver, Escherichia coli, Helix pomatia, and Patella vulgata) to hydrolyze certain steroid glucosiduronic acids." J Biol Chem 236;996-1001. PMID: 13782588

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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