MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical ReactionsProtein-Modification Reactions
Reactions Classified By SubstrateMacromolecule ReactionsProtein-ReactionsProtein-Modification Reactions

EC Number:

Enzymes and Genes:

Escherichia coli K-12 substr. MG1655: biotin carboxylaseInferred from experiment: accC
Homo sapiens: acetyl-CoA carboxylase 1
acetyl-CoA carboxylase 2: ACC2

In Pathway: biotin-carboxyl carrier protein assembly

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: biotin carboxylase

Enzyme Commission Synonyms: biotin carboxylase (component of acetyl CoA carboxylase)

Standard Gibbs Free Energy (ΔrG in kcal/mol): 19.045227Inferred by computational analysis [Latendresse13]

Citations: [Dimroth70]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R04385

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:, UniProt:RELATED-TO:O04983, UniProt:RELATED-TO:O23960, UniProt:RELATED-TO:O52602, UniProt:RELATED-TO:O67483, UniProt:RELATED-TO:O81273, UniProt:RELATED-TO:P24182, UniProt:RELATED-TO:P43873, UniProt:RELATED-TO:Q9CHF3, UniProt:RELATED-TO:Q9JW07, UniProt:RELATED-TO:Q9PN09, UniProt:RELATED-TO:Q9R9I4, UniProt:RELATED-TO:Q06862, UniProt:RELATED-TO:Q39825, UniProt:RELATED-TO:Q42777, UniProt:RELATED-TO:Q58626


Dimroth70: Dimroth P, Guchhait RB, Stoll E, Lane MD (1970). "Enzymatic carboxylation of biotin: molecular and catalytic properties of a component enzyme of acetyl CoA carboxylase." Proc Natl Acad Sci U S A 67(3);1353-60. PMID: 4922289

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Fri Nov 27, 2015, biocyc12.