|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 188.8.131.52
Enzymes and Genes:
5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase : hpaG ( Escherichia coli W )
In Pathway: 4-hydroxyphenylacetate degradation
Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase
Enzyme Commission Synonyms: 5-carboxymethyl-2-oxo-hex-3-ene-1,6-dioate decarboxylase, 5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 7.742325 [Latendresse13]
Unification Links: KEGG:R04380
GarridoPeritier81: Garrido-Peritierra A, Cooper RA (1981). "Identification and purification of distinct isomerase and decarboxylase enzymes involved in the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli." Eur J Biochem 1981;117(3);581-4. PMID: 7026235
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