Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 4.1.1.68

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 4.1.1.68

Enzymes and Genes:
5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase Inferred from experiment : hpaG ( Escherichia coli W )

In Pathway: 4-hydroxyphenylacetate degradation

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase

Enzyme Commission Synonyms: 5-carboxymethyl-2-oxo-hex-3-ene-1,6-dioate decarboxylase, 5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 7.742325 Inferred by computational analysis [Latendresse13]

Citations: [GarridoPeritier81]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R04380

Relationship Links: BRENDA:EC:4.1.1.68 , ENZYME:EC:4.1.1.68 , IUBMB-ExplorEnz:EC:4.1.1.68


References

GarridoPeritier81: Garrido-Peritierra A, Cooper RA (1981). "Identification and purification of distinct isomerase and decarboxylase enzymes involved in the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli." Eur J Biochem 1981;117(3);581-4. PMID: 7026235

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, biocyc11.