Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 3.5.1.23

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.5.1.23

Enzymes and Genes:
N-acylsphingosine amidohydrolase 1 Inferred from experiment : Asah1 ( Mus musculus )
N-acylsphingosine amidohydrolase (alkaline ceramidase) 3 Inferred from experiment : Asah3 ( Mus musculus )
N-acylsphingosine amidohydrolase 2 Inferred from experiment : Asah2 ( Mus musculus )

In Pathway: sphingosine and sphingosine-1-phosphate metabolism

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: ceramidase

Enzyme Commission Synonyms: acylsphingosine deacylase, glycosphingolipid ceramide deacylase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 368.67322 Inferred by computational analysis [Latendresse13]

Citations: [Nilsson69, Yavin69]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R01493 , Rhea:20856

Relationship Links: BRENDA:EC:3.5.1.23 , ENZYME:EC:3.5.1.23 , IUBMB-ExplorEnz:EC:3.5.1.23


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Nilsson69: Nilsson A (1969). "The presence of spingomyelin- and ceramide-cleaving enzymes in the small intestinal tract." Biochim Biophys Acta 176(2);339-47. PMID: 5775951

Yavin69: Yavin E, Gatt S (1969). "Enzymatic hydrolysis of sphingolipids. 8. Further purification and properties of rat brain ceramidase." Biochemistry 8(4);1692-8. PMID: 5805303


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Wed Nov 26, 2014, biocyc13.